File:Viruses-13-00027-v2 - Isolation and Characterization of Salmonella Jumbo-Phage pSal-SNUABM-04.pdf
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[edit]DescriptionViruses-13-00027-v2 - Isolation and Characterization of Salmonella Jumbo-Phage pSal-SNUABM-04.pdf |
English: Isolation and Characterization of Salmonella Jumbo-Phage pSal-SNUABM-04. Viruses 2021, 13(1), 27;doi:10.3390/v13010027. This article belongs to the Special Issue Giant or Jumbo Phages. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
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https://www.mdpi.com/1999-4915/13/1/27/htm Viruses 2021, 13(1), 27;doi:10.3390/v13010027. This article belongs to the Special Issue Giant or Jumbo Phages. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
Author | Jun Kwon, Sang Guen Kim, Hyoun Joong Kim, Sib Sankar Giri, Sang Wha Kim, Sung Bin Lee, Se Chang Park. Academic Editor: Dann Turner |
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Short title | Isolation and Characterization of Salmonella Jumbo-Phage pSal-SNUABM-04 |
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Image title | The increasing emergence of antimicrobial resistance has become a global issue. Therefore, many researchers have attempted to develop alternative antibiotics. One promising alternative is bacteriophage. In this study, we focused on a jumbo-phage infecting Salmonella isolated from exotic pet markets. Using a Salmonella strain isolated from reptiles as a host, we isolated and characterized the novel jumbo-bacteriophage pSal-SNUABM-04. This phage was investigated in terms of its morphology, host infectivity, growth and lysis kinetics, and genome. The phage was classified as Myoviridae based on its morphological traits and showed a comparatively wide host range. The lysis efficacy test showed that the phage can inhibit bacterial growth in the planktonic state. Genetic analysis revealed that the phage possesses a 239,626-base pair genome with 280 putative open reading frames, 76 of which have a predicted function and 195 of which have none. By genome comparison with other jumbo phages, the phage was designated as a novel member of Machinavirus composed of Erwnina phages. |
Author | Jun Kwon, Sang Guen Kim, Hyoun Joong Kim, Sib Sankar Giri, Sang Wha Kim, Sung Bin Lee and Se Chang Park |
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Software used | LaTeX with hyperref |
Conversion program | pdfTeX-1.40.21 |
Encrypted | no |
Page size | 595.276 x 841.89 pts (A4) |
Version of PDF format | 1.7 |
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