User talk:Edgar181/Archive 2017

Big list of (*extremely humbly*) requested cocaine analogue SVGs

Well here's my (maybe) "by next Christmas" list. Probably a few RTIs on my page that Singh didn't have (I'll worry over that sometime further down the yellow Wik-road), and of course if you see what can be taken care of with R-substitutions images in the interim I'll also find those useful. ;-j Nagelfar (talk) 00:27, 7 February 2016 (UTC)

Hey Ed, these should be the final "next Christmas wish list" installment that finally hits every nail into that foundation which I was meaning since the beginning, let me know if there's anything interesting I can do for you where images aren't the factor. In the meantime, this is mostly ones for the page I started myself before user Nuklear got all segued into the phenyltropanes specifically. Thanks! Nagelfar (talk) 22:43, 14 June 2017 (UTC)

These were in a patent with phenyltropanes, some kinda piperazine homologue with a distal nitrogen? (3 total) File:Ring opened phenyltropane analog A.svg File:Ring opened phenyltropane analog B.svg File:Ring opened phenyltropane analog C.svg

Cocaine Analogs and structural-analogous-non-phenyl:

• Has coke analog 196c Been Wrong, all this time? < is the isopropyl one methylene length too long? (1 total) Fixed
• the benzene spirocyclic you made for me, upon finding the whole paper on the topic, appears that, that one, doesn't have the beta oriented C2-tropane carbmethoxy (as is commonly more active in the PT class generally), but rather, alpha oriented (1 correction? total) Fixed
• C4-(chloro)substituted 2/3-unsat. phenylsulfanyl, switched nitrogen 1S 3/5R, switched nitrogen 1R 3/5S ortho-phenyl-benzoyloxy switched-position-nitrogen, tricyclo-C3 OBz, 5-benzoatic azabornane, 6-benzoatic azabornane non-PT cocaine-analogs proper (7 total) Done

//////////////////////////////
(Thanks Ed! This is almost, all of the way, finished(!!)) Nagelfar (talk) 20:47, 16 October 2017 (UTC)

• very simple: it appears the elements (oxygen, etc.) are given in white instead of transparent in: Cocaine analog 400 intermediate.svg, please update

• (Benzene-)Spirocyclics; aren't cmpnd 7 & 8 the same? chemicalize.org renders them as the same if not 8 cause it looks like this is 7, also the additional spirocyclics 12—15 and I suppose those are covered in this substitution image (except that the former appear to be alpha oriented @ C2, whereas the subst. image gives either?.) (5 total) 7 and 8 are Endo-exo isomers, here is 8: File:Spirocyclic_cocaine_analog.svg. Others are File:Spirocyclic cocaine analog 12.svg, etc.

Got 'em, thanks! Nagelfar (talk) 17:41, 26 October 2017 (UTC)

• (non-benzene-)Spirocyclics 4a—12b (23 total) 23 more done: File:Dallanoce 4a.svg ... etc. Ed (Edgar181) 01:59, 29 October 2017 (UTC)

OK got 'em. Nagelfar (talk) 17:04, 31 October 2017 (UTC)

• JHC 1-64, found this one too. — Preceding unsigned comment added by Nagelfar (talk • contribs) 22:11, 5 November 2017 (UTC)
• 'nother "hot mess" (i.e. mid-synth benzene decay) ;-p (1 total) Thanks Ed, hope I'm not getting too overwhelming ;-p Nagelfar (talk) 18:16, 15 May 2016 (UTC)

• • (43 ultimate subtotal remaining)

doi:10.1016/j.bmcl.2012.08.046 interesting cocaine functional analog sigmaergics] (I think you got me these, didn't you? Nagelfar (talk) 17:04, 31 October 2017 (UTC))

I replaced a sci-hub link in the above message with a DOI link because sci-hub links are blacklisted. DMacks (talk) 12:16, 17 October 2018 (UTC)

Benztropines & GBRs

• 3-CPMT
• the 3 JJCs, and R of the MFZ, and PG01053

An R-substitution image for UMB38 and chloro-substituted analogues in regard to their closeness to this and the GBR analogs would be appreciated too.
(From the above thanks, to here, and I can't for the life of me imagine anything more thoroughly complete in this class than what me and you have put in WP, can't think of anything more to even include(!!... sure I'll find something eventually, but it won't look so daunting one-at-a-time) ;-)) Nagelfar (talk) 20:47, 16 October 2017 (UTC)
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(cf. the edit history for omitted conversation; cleaned up for practical work purposes regarding easy reference ;-j)

Wrapped Redundant .pngs of above covered cmpds: click to show

F&B series (Biotin side-chains etc.) (Same examples are already there, at least some of them, at the linked "png → svg" below in the original remainder of this 'to-do' list, but they aren't in accord to the consistency of MoS like the rest of your images.) RTI-224, RTI-233, RTI-235, RTI-236, RTI-237, RTI-244, RTI-245, RTI-246, RTI-248, RTI-249, RTI-266, RTI-267, RTI-268, RTI-269 <-- I can't figure out the structure of these compounds from the table in List of phenyltropanes <--They're given below (which I now moved up here), I will check the partial images below the table; e.g. F1, B3, F8; they correspond; I'll try to get them together myself, in the meantime do the above, — Preceding unsigned comment added by Nagelfar (talk • contribs) 05:02, 15 January 2017 (UTC) I uploaded versions myself, still, they don't have your svg magic touch ;-p I was hoping if these ever get to the priority list you could do abox multi-image like the thiophenes you did for me consisting of a single svg of the following: File:Biotin_sidechain_bi-cyclopentane_N-methyl_phenyltropane.png, File:Biotin_sidechain_bi-cyclopentane_phenyltropane.png, File:Biotin_sidechain_carbethoxy_N-methyl_phenyltropane.png, File:Biotin_sidechain_long_fourteen_methylene_unit_phenyltropane.png, File:Biotin_sidechain_long_ten_methylene_unit_phenyltropane.png, File:Biotin_sidechain_long_twelve_methylene_unit_phenyltropane.png, File:Biotin_sidechain_N-acyl_di-N-methyl_phenyltropane.png, File:Biotin_sidechain_parachloro_N-methyl_phenyltropane.png, File:Biotin_sidechain_parachloro_phenyltropane.png, File:Biotin_sidechain_paramethyl_N-methyl_phenyltropane.png, File:Biotin_sidechain_paramethyl_phenyltropane.png, File:Biotin_sidechain_phenylethyl_bi-cyclopentane_phenyltropane.png, File:Biotin_sidechain_phenylethyl_parachloro_phenyltropane.png, File:Biotin_sidechain_phenylethyl_phenyltropane.png— Preceding unsigned comment added by Nagelfar (talk • contribs) 19:07, 10 May 2017 (UTC)

Wrapped conversation: click to show

I'll try to get to them and some of the others below soon. Ed (Edgar181) 16:50, 1 January 2017 (UTC) wait, before that I found an error, either on your end or possibly in the table: RTI-157 you drew as para-H, but the table says it's p-Methyl. Nagelfar (talk) 17:49, 5 January 2017 (UTC) @Nagelfar: Looks like my error. I uploaded a correction. Ed (Edgar181) 23:12, 13 January 2017 (UTC) To do: RTI-240 Is rendered the same as RTI-145 (2-position of RTI-240 is -CHMe2 whereas RTI-145 2-pos. is -CH2OCO2Me. Nagelfar (talk) 21:32, 14 January 2017 (UTC) OK, fixed now. Ed (Edgar181) 23:49, 14 January 2017 (UTC) RTI-319 Previously done: File:RTI-319.svg The one so-named as "napthyl" is, with same said name; but on the "Enantioselective nonstandard configurations (non-2β-,3β-)" table is one that is a "Bn" (instead of "3α-2-naphthyl") which is as described from U.S. Patent# 7,011,813. Maybe find a better name for file to accommodate. Nagelfar (talk) 20:55, 14 January 2017 (UTC) I have uploaded one with a benzyl group at File:RTI-319 alt.svg. Ed (Edgar181) 23:49, 14 January 2017 (UTC) pg. 957 (33rd) R-97a & R-97b ('cause interm. synth. of benzene is intriguing hot mess ;-p ) (2 total) Missed the second one tho' you scratched it; I made a .png of R-97b, there are more important things below so I am not too worried ;-) interest must be waning, thanks for the effort despite that. Nagelfar (talk) 21:32, 14 January 2017 (UTC) I created it, but somehow missed uploading that one. Ed (Edgar181) 23:49, 14 January 2017 (UTC) An R-substitution image for UMB38 and chloro-substituted analogues in regard to their closeness to this and the GBR analogs would be appreciated too. Nagelfar (talk) 22:06, 1 June 2016 (UTC) @Nagelfar: I've done a few more. I'll try to get to even more this evening. If you want "prioritize" any set, please feel free to just move them up the list and I'll just continue to work down from the top. Ed (Edgar181) 21:45, 13 July 2016 (UTC) Awesome. I'll leave them as is for now, the Tamagnan ones pique my interest, but I really want the Singh images to get seen to completion. ;-j thanks as always Ed. Nagelfar (talk) 02:46, 15 July 2016 (UTC) Eh, those Tamagnan are sticking out too much like a sore thumb, gotta get 'em outta the way or they'll drive me crazy. ;-P Nagelfar (talk) 19:44, 16 July 2016 (UTC) Was indisposed for the last month and a half, but came back to see you've had some waiting for me; I got them added to their articles, I thank you as always! Nagelfar (talk) 20:24, 21 September 2016 (UTC)

Wrapped (most recent) conversation/finished-work: click to show

, RTI-370 <-- @Nagelfar: RTI-262 and RTI-370 have vague or missing descriptions in the table in List of phenyltropanes <-I'll see if I can find more on 'em, in the meantime I have two more below:Nagelfar RTI-370 is apparently in this journal as screen captured. Nagelfar (talk) 02:12, 15 January 2017 (UTC) pg. 958 (34th) R/S-98a—R/S-98c' (3 total) pg. 959 (35th) 103a—103c & 104a—104d (7 total) Thanks Ed Nagelfar (talk) 19:26, 16 January 2017 (UTC) PRE-EMPT PRIORITY: en:Substituted phenylmorpholine Got 'em myself. (mostly 'cause didn't want to take your helping me away from my magnum opus.) ;-j(User talk:Nagelfar pg. 961 (37th) 121a—121n (14 total) pg. 961 (37th) (±)-122a—(±)-122j (10 total) pg. 963 (39th) just *140 (whew! eh? ;-j ) (1 total) 3β-(4-alkylthiophenyl)nortropanes i.e. 8a → 11b (10 total)

RTI-262 (still have to find this structure, skip for now.)

Information template missing

Hi Ed. Would you mind having a look at the two dozens of your files (mostly transferred from Wikipedia by other users) without the Information template (incategory:Media_missing_infobox_template Edgar181)? Some of them may have been replaced by newer versions. --Leyo 12:53, 27 January 2017 (UTC)

Yes, I will take a look at them all and either add the information template to them or delete them if they aren't currently useful. Ed (Edgar181) 14:37, 27 January 2017 (UTC)

File:4-acetoxy-dipt.png

File:4-acetoxy-dipt.png has been listed at Commons:Deletion requests so that the community can discuss whether it should be kept or not. We would appreciate it if you could go to voice your opinion about this at its entry. If you created this file, please note that the fact that it has been proposed for deletion does not necessarily mean that we do not value your kind contribution. It simply means that one person believes that there is some specific problem with it, such as a copyright issue. Please see Commons:But it's my own work! for a guide on how to address these issues. Please remember to respond to and – if appropriate – contradict the arguments supporting deletion. Arguments which focus on the nominator will not affect the result of the nomination. Thank you!

DMacks (talk) 02:17, 2 February 2017 (UTC)

NMDA drug that is 30 times potency of ketamine w/ a 10+ hr. half-life

here it is: lower image

BL org post about it

patent referenceable mentioning it in attestable WP qualifying manner

Maybe do a svg of it, labeled by its IUPAC, and I'll start its article Nagelfar (talk) 21:45, 15 March 2017 (UTC)

Here it is: file:N-methylhexahydrofluorenamine.svg. Ed (Edgar181) 14:23, 18 March 2017 (UTC)

I'll get to making the page, haven't forgot about this at this point ;j Nagelfar (talk) 17:44, 1 April 2017 (UTC)

done. Cheers. Nagelfar (talk) 19:11, 4 April 2017 (UTC)

Commons:Deletion requests/File:Benzen metabolizm.gif

Hi Edgar181. The SVG version was included to that DR. I guess would need to take a decision there, too. --Leyo 13:50, 28 March 2017 (UTC)

I intended to delete the svg too, but somehow missed it. It is done now. Thanks for letting me know. Ed (Edgar181) 13:52, 28 March 2017 (UTC)

Rucaparib

The compound is clearly an indole but User:Flyer22 Reborn undid my removal of a very very poorly written paper claiming it's a benzimdiazole. When you get a chance can you rewrite that section? 69.125.168.63 05:13, 2 May 2017 (UTC)

It looks like the inaccurate benzimidazole comment is no longer in the article. I'll keep an eye on it to make sure it doesn't return. Ed (Edgar181) 13:49, 2 May 2017 (UTC)

Request for svgs

Simple request to make svg images of the structures on this page: https://en.wikipedia.org/wiki/Sodium_dodecylbenzenesulfonate — Preceding unsigned comment added by Mfernflower (talk • contribs) 01:17, 5 June 2017 (UTC)

No problem. I should be able to find the time to do them within a day or so. Ed (Edgar181) 16:25, 5 June 2017 (UTC)

 Done. I created File:Sodium dodecylbenzenesulfonate skeletal.svg and File:Sodium dodecylbenzenesulfonate branched.svg. Ed (Edgar181) 22:00, 6 June 2017 (UTC)

Ashwagandha (Withania somnifera) alkaloids (also known as poison gooseberry or winter cherry)

I notice how you've focused on estrogen analogues and such in recent history, Ed. Well I have taken interest in 'Ashwagandha' extract, which contains, among other things, Withaferin A steroidal lactone with many different other human metabolic affectations. The plant also has many alkaloids shared with the nightshade and tropane families; but it has two in particular I am quite interested in, exclusive to the plant itself which have no pages on WP, and they are ashwagandhine, ashwaganidhine, and somniferine, known exclusively from this plant and not attested to be known in others. If you have a source to find the structures for those three, could you draw them? Nagelfar (talk) 23:16, 15 July 2017 (UTC)

Someone came up with one of them, as part of the poppy constituent: Somniferine. Nagelfar (talk) 20:20, 24 July 2017 (UTC)

I haven't been too active on Wikipedia lately, but I'll try to get to them soon. Ed (Edgar181) 19:46, 10 August 2017 (UTC)

@Nagelfar: Sorry I've been slow. Here is an image for somniferine: File:Somniferine.svg. At the moment, I can't find out the chemical structures of ashwagandhine and ashwaganidhine. I'll keep looking. Ed (Edgar181) 15:35, 27 August 2017 (UTC)

Thanks old friend, it's on the List of opioids dimer table at the bottom of the pop-up table-list of images, now. Nagelfar (talk) 01:30, 30 August 2017 (UTC)

Commons Conference project

Hello

I'm writing you as one of the most active Commons users right now. Since a while now, the idea of a dedicated Commons conference has been floating around. But since the last Wikimania concrete steps have been taken to actually make it happen next year. If you're interested in participation or maybe willing to help organize the first ever Commons Conference, I invite you to check out the project page and leave your comments; or just show your support for the idea, by signing up.

Cheers,

--Touzrimounir (talk) 22:15, 6 September 2017 (UTC)

Upcoming Wiki Science Competition

Hi, I am contacting all active commons users I can find more interested in the management of pictures related to scientific topics. If you have time, could you take a look in Commons:Village_pump#Upcoming_Wiki_Science_Competition. Thank you.--Alexmar983 (talk) 07:26, 17 September 2017 (UTC)

Standard date format

Hi Edgar, could you please use the ISOdate format for you future uploads? So i do not need to clean them up. [1]. Thank you for your cooperation, --ArndBot (talk) 14:53, 27 September 2017 (UTC)

I currently use Wikimedia's automated method of generating the current date (~~~~~). If there is a way to automatically generate the current date in the format you would like, please let me know and I'll use it. Ed (Edgar181) 17:10, 27 September 2017 (UTC)

When uploading chemical structures I use {{subst:CURRENTYEAR}}-{{subst:CURRENTMONTH}} (see ↑ symbol on my user page). You could add the day if you'd like to. --Leyo 22:48, 27 September 2017 (UTC)

Perfect. I'll use that. Thanks. Ed (Edgar181) 23:32, 27 September 2017 (UTC)

I have {{Commons:Upload/Chemistry}} on my userpage so I don't have to remember what an icon represents:) DMacks (talk) 02:40, 28 September 2017 (UTC)

I've been around a long time but have never seen that. :) Thanks. Ed (Edgar181) 11:17, 28 September 2017 (UTC)

Cocaine List, "Big list of", as seen above

Hi Ed. I know life beacons, even at more priority interests as off-time hobbies go in the chemistry world; the above list I wanted to mention FYI, probably won't get much bigger, and I'll then rest easy that it's done to the best among what's published that I can find. ;-) Nagelfar (talk) 22:36, 8 October 2017 (UTC)

OK, I will return to the "Big list" and get a bunch of them done very soon. Mostly I've been distracted by other things, I guess. Ed (Edgar181) 19:05, 9 October 2017 (UTC)

It's a huge endeavor which I am happy to have you on board with, no explanation necessary (I've been livin' life too, well, sorta, lol). Thanks for jumping right back into the high quality of work though, got the lastest added. Nagelfar (talk) 17:12, 16 October 2017 (UTC)

File:Alpha-hederin.svg

Hi Edgar181. Could you please consider adapting the structure based on my note? --Leyo 14:25, 11 October 2017 (UTC)

Fixed. Thanks for letting me know about the error. Ed (Edgar181) 15:22, 11 October 2017 (UTC)

IP intervention

Hi. Can you have a look at Commons:Deletion requests/File:Jason Lin and Peter Huang 2014-03-08.jpg please? Ty. --E4024 (talk) 15:13, 13 October 2017 (UTC)

I protected the page and blocked a couple of the recent IPs. That should help for now. Please let me know if the problem resurfaces in some way. Ed (Edgar181) 15:19, 13 October 2017 (UTC)

Interested in starting a series of morphine 3-ester/ether + 6-ether/esters SVGs?

Should be simple. I notice WP has 3-methylmorphine, 6-methylmorphine, 6-MAM, 6-MAC, 3,6-ThisThat&TheOther; but the potent common mixes, 3-this,6-that; are omitted. Just mono- & di-ester types. I think a subsection of the opioid morphinan lists could use that to such purposes.

we have 3-Monoacetylmorphine, 6-Monoacetylmorphine; plus propionyl, propanoyl, nico, benzoyl, above and beyond the methyl & acetyl that can be either in the 3 or 6 position, every combination thereof might very well be all such an endeavor would consist of at first. — Preceding unsigned comment added by Nagelfar (talk • contribs) 21:30, 22 October 2017 (UTC)

I'd have to delve a bit for which combinations would be viable synthesis-wise; but liable esters with nonliable ethers i.e. 3-methyl,6-acetyl-morphine, might be a start. Nagelfar (talk) 18:43, 22 October 2017 (UTC)

Lithol rubine BK

Hello Edgar, the sulfo group in File:Lithol_Rubine.png should not be ortho, but meta to the methyl group. --FK1954 (talk) 10:08, 25 October 2017 (UTC)

I have now replaced it with File:Lithol rubine BK.svg. Thanks for catching the error and letting me know. Ed (Edgar181) 11:51, 25 October 2017 (UTC)

And thank you for your rapid reaction! --FK1954 (talk) 14:06, 25 October 2017 (UTC)

File:1,2,3-trichlorobenzene.png

File:1,2,3-trichlorobenzene.png has been listed at Commons:Deletion requests so that the community can discuss whether it should be kept or not. We would appreciate it if you could go to voice your opinion about this at its entry. If you created this file, please note that the fact that it has been proposed for deletion does not necessarily mean that we do not value your kind contribution. It simply means that one person believes that there is some specific problem with it, such as a copyright issue. Please see Commons:But it's my own work! for a guide on how to address these issues. Please remember to respond to and – if appropriate – contradict the arguments supporting deletion. Arguments which focus on the nominator will not affect the result of the nomination. Thank you!

109.238.80.47 22:17, 13 November 2017 (UTC)

Apalutamide formula

Hello, the benzene ring with cyano group in apalutamide formula should actually be a pyridine ring. prohnily — Preceding unsigned comment was added by 193.202.91.11 (talk) 07:46, 23 November 2017 (UTC)

Somebody replaced my image with an incorrect one. I have restored the correct original. Thanks for catching the problem and letting me know. Ed (Edgar181) 14:32, 24 November 2017 (UTC)