File:Sexual differentiation of bipotential gonads and the histological variations of ovaries in the indicated species.png
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| Description | Figure 3. Sexual differentiation of bipotential gonads and the histological variations of ovaries in the indicated species. (A) Bipotential gonads differentiate into testes or ovaries. In mammalian testes, primary sex cords form tubular structures (seminiferous tubules (deep blue) with germ cells (yellow dots)) and the rete testis (cyan), which provide a route for continuous sperm transportation from the seminiferous tubules to the efferent ducts. Interstitial components are shown in gray. Mammalian ovaries commonly develop secondary sex cords with germ cells in the cortical region as a site of future folliculogenesis (orange; yellow dots, germ cells). However, the morphological characteristics of primary sex cords in the medullary region of the ovary show considerable diversity among mammals. (B) In the ovaries of goats and cows, secondary sex cords in the cortical region form during the fetal period. Germ cells in the medullary region disappear and the primary sex region regresses. In the ovaries of mice, secondary sex cords in the cortical region are not distinct in the fetal period; germ cells in the medullary region are maintained and develop immediately after birth as the first wave of follicles (pale-orange circles with yellow dots). In the ovaries of spotted hyenas and most mole species, the medullary region develops as a male-like tissue with Leydig-cell-like steroidogenic cells (deep blue). In the ovaries of horses, the cortical region (in which folliculogenesis occurs) is surrounded by the well-developed medulla and forms a unique structure known as the ovulation fossa. |
| Date | |
| Source | https://www.researchgate.net/publication/365064403_Gonadal_Sex_Differentiation_and_Ovarian_Organogenesis_along_the_Cortical-Medullary_Axis_in_Mammals Gonadal Sex Differentiation and Ovarian Organogenesis along the Cortical–Medullary Axis in Mammals. Int. J. Mol. Sci. 2022,23, 13373. https://doi.org/10.3390/ijms232113373 |
| Author | Imaimatsu, K.; Uchida, A.; Hiramatsu, R.; Kanai, Y. |
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This file, which was originally posted to an external website, has not yet been reviewed by an administrator or reviewer to confirm that the above license is valid. See Category:License review needed for further instructions.
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Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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| Description | Figure 2. Sertoli-Leydig cell tumor with cords and Leydig cell nests (A, HE stain) with a profile GATA-4 positive (B) and FOG-2 positive: thick arrow, Leydig cells FOG-2 negative; thin arrow, Sertoli cells FOG-2 positive (C). |
| Date | |
| Source | https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0045914 GATA-4 and FOG-2 Expression in Pediatric Ovarian Sex Cord-Stromal Tumors Replicates Embryonal Gonadal Phenotype: Results from the TREP Project. PLoS ONE 7(9): e45914. https://doi.org/10.1371/journal.pone.0045914 |
| Author | Virgone C, Cecchetto G, Ferrari A, Bisogno G, Donofrio V, Boldrini R, et al. |
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This file, which was originally posted to an external website, has not yet been reviewed by an administrator or reviewer to confirm that the above license is valid. See Category:License review needed for further instructions.
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© Virgone et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Licensing
[edit]
This file is licensed under the Creative Commons Attribution 4.0 International license.
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
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| current | 00:41, 5 July 2024 | | 3,342 × 2,383 (1.12 MB) | Rasbak (talk | contribs) | |
| 17:39, 4 July 2024 |  | 850 × 606 (305 KB) | Rasbak (talk | contribs) | {{Information |description= Figure 3. Sexual differentiation of bipotential gonads and the histological variations of ovaries in the indicated species. (A) Bipotential gonads differentiate into testes or ovaries. In mammalian testes, primary sex cords form tubular structures (seminiferous tubules (deep blue) with germ cells (yellow dots)) and the rete testis (cyan), which provide a route for continuous sperm transportation from the seminiferous tubules to the efferent ducts. Interstitial comp... |
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