File:Cucurbitacin-I-Inhibits-Cell-Motility-by-Indirectly-Interfering-with-Actin-Dynamics-pone.0014039.s006.ogv
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[edit]DescriptionCucurbitacin-I-Inhibits-Cell-Motility-by-Indirectly-Interfering-with-Actin-Dynamics-pone.0014039.s006.ogv |
English: F-actin formation in the presence of cucurbitacin I in low-density MDCK cell cultures. MDCK cells expressing mCherry-actin were seeded on a laminin-coated dish at low density and allowed to attach. The cells were imaged at 37°C by DIC and epifluorescence every 1 min before and after the addition of 200 nM cucurbitacin I. The movie begins just after the addition of the compound to the cells. The formation of aggregates of actin over the following 5 h can be seen. |
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Source | Movie S5 from Knecht D, LaFleur R, Kahsai A, Argueta C, Beshir A, Fenteany G (2010). "Cucurbitacin I Inhibits Cell Motility by Indirectly Interfering with Actin Dynamics". PLOS ONE. DOI:10.1371/journal.pone.0014039. PMID 21124831. PMC: 2991314. | ||
Author | Knecht D, LaFleur R, Kahsai A, Argueta C, Beshir A, Fenteany G | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 15:16, 30 October 2012 | 21 s, 1,114 × 460 (13.17 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Knecht D, LaFleur R, Kahsai A, Argueta C, Beshir A, Fenteany G |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2010 |
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2010
application/ogg
30db6c1c50fb5b9ca7c31bb7c5e93eead9749bb1
13,812,815 byte
20.8 second
460 pixel
1,114 pixel
Categories:
- Videos of cell signaling
- Videos of chemical biology of the cell
- Microfilaments
- Actin depolymerizing factors
- Actin video
- Antineoplastic agents
- Tumor cell line
- Cell movement
- Videos of the cytoskeleton
- Depsipeptides
- Dictyostelium
- Drug dose-response relationship
- Gelsolin
- Confocal microscopic movies from Open Access Journals
- Cyclic peptides
- Videos of triterpenes
- Media from PLOS ONE
- MCherry