File:Cucurbitacin-I-Inhibits-Cell-Motility-by-Indirectly-Interfering-with-Actin-Dynamics-pone.0014039.s004.ogv

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Cucurbitacin-I-Inhibits-Cell-Motility-by-Indirectly-Interfering-with-Actin-Dynamics-pone.0014039.s004.ogv(Ogg Theora video file, length 50 s, 768 × 576 pixels, 1.15 Mbps, file size: 6.85 MB)

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English: B16-F1 cells exposed to cucurbitacin I immediately stop protrusion and begin retraction of lamellae. B16-F1 cells were imaged at 37°C every 30 s for 3 h by phase-contrast microscopy and then cucurbitacin I was added to 200 nM while imaging. The movie shows the 8 min prior to compound addition and the next 40 min in the presence of compound. The freezing of protrusion is evident within a minute after addition of compound, while retraction took place over a longer time scale.
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Source Movie S3 from Knecht D, LaFleur R, Kahsai A, Argueta C, Beshir A, Fenteany G (2010). "Cucurbitacin I Inhibits Cell Motility by Indirectly Interfering with Actin Dynamics". PLOS ONE. DOI:10.1371/journal.pone.0014039. PMID 21124831. PMC: 2991314.
Author Knecht D, LaFleur R, Kahsai A, Argueta C, Beshir A, Fenteany G
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This file was published in a Public Library of Science journal. Their website states that the content of all PLOS journals is published under the Creative Commons Attribution 4.0 license (or its previous version depending on the publication date), unless indicated otherwise.
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Date/TimeThumbnailDimensionsUserComment
current15:15, 30 October 201250 s, 768 × 576 (6.85 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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VP9 480P 349 kbps Completed 00:32, 23 August 2018 24 s
Streaming 480p (VP9) 349 kbps Completed 08:32, 25 January 2024 1.0 s
VP9 360P 189 kbps Completed 00:32, 23 August 2018 16 s
Streaming 360p (VP9) 189 kbps Completed 23:13, 5 February 2024 1.0 s
VP9 240P 96 kbps Completed 00:32, 23 August 2018 14 s
Streaming 240p (VP9) 97 kbps Completed 00:19, 16 December 2023 1.0 s
WebM 360P 509 kbps Completed 04:34, 13 November 2012 27 s
Streaming 144p (MJPEG) 348 kbps Completed 17:23, 2 November 2023 1.0 s

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