Category:Media from Desquenes et al 2016 - 10.1051/parasite/2016001
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(2016). "Refractory hypoglycaemia in a dog infected with Trypanosoma congolense". Parasite 23: 1. DOI:10.1051/parasite/2016001. ISSN 1776-1042.
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Abstract
A 20 kg German shepherd dog was presented to a French veterinary teaching hospital for seizures and hyperthermia. The dog had returned 1 month previously from a six-month stay in Senegal and sub-Saharan Africa. Biochemistry and haematology showed severe hypoglycaemia (0.12 g/L), anaemia and thrombocytopenia. Despite administration of large amounts of glucose (30 mL of 30% glucose IV and 10 mL of 70% sucrose by gavage tube hourly), 26 consecutive blood glucose measurements were below 0.25 g/L (except one). Routine cytological examination of blood smears revealed numerous free extracytoplasmic protozoa consistent with Trypanosoma congolense. PCR confirmed a Trypanosoma congolense forest-type infection. Treatment consisted of six injections of pentamidine at 48-hour intervals. Trypanosomes had disappeared from the blood smears four days following the first injection. Clinical improvement was correlated with the normalization of laboratory values. The infection relapsed twice and the dog was treated again; clinical signs and parasites disappeared and the dog was considered cured; however, 6 years after this incident, serological examination by ELISA T. congolense was positive. The status of this dog (infected or non-infected) remains unclear. Hypoglycaemia was the most notable clinical feature in this case. It was spectacular in its severity and in its refractory nature; glucose administration seemed only to feed the trypanosomes, indicating that treatment of hypoglycaemia may in fact have been detrimental.
Media in category "Media from Desquenes et al 2016 - 10.1051/parasite/2016001"
The following 6 files are in this category, out of 6 total.
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Parasite150045-fig1 Dog with Trypanosoma congolense.tif 1,171 × 878; 1.8 MB
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Parasite150045-fig2 Dog with Trypanosoma congolense.tif 1,171 × 773; 1.01 MB
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Parasite150045-fig3 Dog with Trypanosoma congolense.tif 1,171 × 774; 820 KB
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Parasite150045-fig4 Dog with Trypanosoma congolense.png 1,308 × 767; 27 KB
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Parasite150045-fig5 Dog with Trypanosoma congolense.png 670 × 589; 18 KB
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Parasite150045-fig6 Dog with Trypanosoma congolense.tif 1,171 × 839; 567 KB
