File:Targeting-Cx43-and-N-Cadherin-Which-Are-Abnormally-Upregulated-in-Venous-Leg-Ulcers-Influences-pone.0037374.s008.ogv
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Size of this JPG preview of this OGG file: 800 × 407 pixels. Other resolutions: 320 × 163 pixels | 846 × 430 pixels.
Original file (Ogg Theora video file, length 5.1 s, 846 × 430 pixels, 898 kbps, file size: 564 KB)
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[edit]DescriptionTargeting-Cx43-and-N-Cadherin-Which-Are-Abnormally-Upregulated-in-Venous-Leg-Ulcers-Influences-pone.0037374.s008.ogv |
English: Cx43-DN transfected cells migrate faster than Cx43-WT or eGFP-transfected cells after wounding. Fibroblasts were transiently transfected with bicistronic pIRES-GFP expression vectors encoding Cx43-WT, Cx43-DN or eGFP alone. The migration rates were monitored for 3 h and time-lapse images were taken at 5 min intervals. Cells transfected with the Cx43-DN migrated faster than their respective controls, and also extended a large lamellipodial membrane protrusion at the leading edge in the direction of the migration. |
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Source | Movie S3 from Mendoza-Naranjo A, Cormie P, Serrano A, Hu R, O'Neill S, Wang C, Thrasivoulou C, Power K, White A, Serena T, Phillips A, Becker D (2012). "Targeting Cx43 and N-Cadherin, Which Are Abnormally Upregulated in Venous Leg Ulcers, Influences Migration, Adhesion and Activation of Rho GTPases". PLOS ONE. DOI:10.1371/journal.pone.0037374. PMID 22615994. PMC: 3352877. | ||
Author | Mendoza-Naranjo A, Cormie P, Serrano A, Hu R, O'Neill S, Wang C, Thrasivoulou C, Power K, White A, Serena T, Phillips A, Becker D | ||
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current | 11:27, 15 November 2012 | 5.1 s, 846 × 430 (564 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Mendoza-Naranjo A, Cormie P, Serrano A, Hu R, O'Neill S, Wang C, Thrasivoulou C, Power K, White A, Serena T, Phillips A, Becker D |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Cx43-DN transfected cells migrate faster than Cx43-WT or eGFP-transfected cells after wounding. Fibroblasts were transiently transfected with bicistronic pIRES-GFP expression vectors encoding Cx43-WT, Cx43-DN or eGFP alone. The migration rates were monitored for 3 h and time-lapse images were taken at 5 min intervals. Cells transfected with the Cx43-DN migrated faster than their respective controls, and also extended a large lamellipodial membrane protrusion at the leading edge in the direction of the migration. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2012 |