File:Regulated-Fluctuations-in-Nanog-Expression-Mediate-Cell-Fate-Decisions-in-Embryonic-Stem-Cells-pbio.1000149.s007.ogv
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Regulated-Fluctuations-in-Nanog-Expression-Mediate-Cell-Fate-Decisions-in-Embryonic-Stem-Cells-pbio.1000149.s007.ogv (Ogg Theora video file, length 16 s, 800 × 600 pixels, 2.03 Mbps, file size: 3.83 MB)
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[edit]DescriptionRegulated-Fluctuations-in-Nanog-Expression-Mediate-Cell-Fate-Decisions-in-Embryonic-Stem-Cells-pbio.1000149.s007.ogv |
English: Stochastic transitions between the HN and LN states. Sorted cells from the plateau between the LN and the HN states were filmed for 50 h. The stochastic nature of the decision is most obvious in the two daughters of the cell marked with a white arrow at 0 h in Figure 5B . One of them up-regulates Nanog/GFP (see yellow arrows in Figure 5B ), whereas the other down-regulates it (black arrows in Figure 5B ). The video shows the first 39 h of this process.
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Source | Video S2 from Kalmar T, Lim C, Hayward P, Muñoz-Descalzo S, Nichols J, Garcia-Ojalvo J, Martinez Arias A, Goodell M. "Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells". PLOS Biology. DOI:10.1371/journal.pbio.1000149. PMID 19582141. PMC: 2700273. | ||
Author | Kalmar T, Lim C, Hayward P, Muñoz-Descalzo S, Nichols J, Garcia-Ojalvo J, Martinez Arias A, Goodell M | ||
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This file is licensed under the Creative Commons Attribution 3.0 Unported license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 18:10, 30 August 2012 | 16 s, 800 × 600 (3.83 MB) | Open Access Media Importer Bot (talk | contribs) | Uploaded with the Open Access Media Importer. (test edit) botrequest |
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Short title | Video S2 |
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Author | |
Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Stochastic transitions between the HN and LN states. Sorted cells from the plateau between the LN and the HN states were filmed for 50 h. The stochastic nature of the decision is most obvious in the two daughters of the cell marked with a white arrow at 0 h in Figure 5B . One of them up-regulates Nanog/GFP (see yellow arrows in Figure 5B ), whereas the other down-regulates it (black arrows in Figure 5B ). The video shows the first 39 h of this process. (4.80 MB AVI) |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2009-07-07 |
Categories:
- Videos of cell differentiation
- P19 cell
- Videos of embryonic stem cells
- Flow cytometry
- Gene expression profiling
- Gene expression regulation
- Gene regulatory networks
- Reporter genes
- Homeodomain proteins
- Octamer transcription factor-3
- Phenotypes
- Pluripotent stem cells
- SOXB1 transcription factors
- Videos of transcription factors
- Transgenes
- Cultured tumor cells