File:Polarised-Asymmetric-Inheritance-of-Accumulated-Protein-Damage-in-Higher-Eukaryotes-pbio.0040417.sv005.ogv
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Polarised-Asymmetric-Inheritance-of-Accumulated-Protein-Damage-in-Higher-Eukaryotes-pbio.0040417.sv005.ogv (Ogg Theora video file, length 48 s, 201 × 201 pixels, 39 kbps, file size: 231 KB)
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DescriptionPolarised-Asymmetric-Inheritance-of-Accumulated-Protein-Damage-in-Higher-Eukaryotes-pbio.0040417.sv005.ogv |
English: Mitosis is Extremely Delayed in Cells with Multiple Inclusions Video of an O23 cell expressing an EGFP-tagged polyglutamine-expanded huntingtin fragment (EGFP-HDQ74) with an aggresome that subsequently forms other inclusions, especially in the nucleus. The cell enters mitosis and completes cytokinesis, but compared to cells with a single aggresome (Figure 3 and Videos S1 and S2), cytokinesis is severely delayed. Images were taken at 10-min intervals, and the frame rate is two images per second. The video corresponds to Figure 3D. |
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Source | Video S5 from Rujano M, Bosveld F, Salomons F, Dijk F, van Waarde M, van der Want J, de Vos R, Brunt E, Sibon O, Kampinga H (2006). "Polarised Asymmetric Inheritance of Accumulated Protein Damage in Higher Eukaryotes". PLOS Biology. DOI:10.1371/journal.pbio.0040417. PMID 17147470. PMC: 1750924. | ||
Author | Rujano M, Bosveld F, Salomons F, Dijk F, van Waarde M, van der Want J, de Vos R, Brunt E, Sibon O, Kampinga H | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 14:12, 16 November 2012 | 48 s, 201 × 201 (231 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Short title | Mitosis is Extremely Delayed in Cells with Multiple Inclusions |
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Author | Rujano M, Bosveld F, Salomons F, Dijk F, van Waarde M, van der Want J, de Vos R, Brunt E, Sibon O, Kampinga H |
Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Video of an O23 cell expressing an EGFP-tagged polyglutamine-expanded huntingtin fragment (EGFP-HDQ74) with an aggresome that subsequently forms other inclusions, especially in the nucleus. The cell enters mitosis and completes cytokinesis, but compared to cells with a single aggresome (Figure 3 and Videos S1 and S2), cytokinesis is severely delayed. Images were taken at 10-min intervals, and the frame rate is two images per second. The video corresponds to Figure 3D. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2006-12 |