File:Parthenogenesis - Bischoff, Steve R 2010.tif
Original file (3,000 × 1,941 pixels, file size: 39.49 MB, MIME type: image/tiff)
Captions
Summary[edit]
DescriptionParthenogenesis - Bischoff, Steve R 2010.tif |
English: Parthenogenetic development of swine oocytes. [(Bischoff et al., 2009), PMID: 19571260]. High metaphase promoting factor (MPF) activity causes mammalian oocytes to arrest at the metaphase II stage until fertilization by a sperm. The fertilization event causes intracellular calcium oscillations, and targeted degradation of cyclin B, a regulatory subunit of MPF, thus permitting the MII-arrested oocyte to proceed through meiosis.
To initiate parthenogenesis of swine oocytes, various methods exist to induce an artificial activation that mimics sperm entry, such as calcium ionophore treatment, microinjection of calcium ions, or electrical stimulation. Treatment with cycloheximide, a non-specific protein synthesis inhibitor, enhances parthenote development in swine presumably by continual inhibition of MPF/cyclin B [(Mori et al., 2008), PMID: 18635923]. As meiosis proceeds, extrusion of the second polar is blocked by exposure to cytochalasin B. This treatment results in a diploid (2 maternal genomes) parthenote. Bischoff, S. R., Tsai, S., Hardison, N., Motsinger-Reif, A. A., Freking, B. A., Nonneman, D., Rohrer, G. and Piedrahita, J. A. (2009) Characterization of conserved and nonconserved imprinted genes in swine. Biol Reprod, 81, 906-920. Mori, H., Mizobe, Y., Inoue, S., Uenohara, A., Takeda, M., Yoshida, M. and Miyoshi, K. (2008) Effects of cycloheximide on parthenogenetic development of pig oocytes activated by ultrasound treatment. J Reprod Dev, 54, 364-369. |
||
Date | |||
Source | Own work | ||
Author | Steve R. Bischoff | ||
Other versions |
|
Licensing[edit]
- You are free:
- to share – to copy, distribute and transmit the work
- to remix – to adapt the work
- Under the following conditions:
- attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
- share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.2 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the section entitled GNU Free Documentation License.http://www.gnu.org/copyleft/fdl.htmlGFDLGNU Free Documentation Licensetruetrue |
File history
Click on a date/time to view the file as it appeared at that time.
Date/Time | Thumbnail | Dimensions | User | Comment | |
---|---|---|---|---|---|
current | 09:10, 12 December 2010 | 3,000 × 1,941 (39.49 MB) | Bremenjock (talk | contribs) | {{Information |Description={{en|1=Parthenogenetic development of swine oocytes. [(Bischoff et al., 2009), PMID: 19571260]. High metaphase promoting factor (MPF) activity causes mammalian oocytes to arrest at the metaphase II stage until fertilization by |
You cannot overwrite this file.
File usage on Commons
There are no pages that use this file.
File usage on other wikis
The following other wikis use this file:
- Usage on en.wikipedia.org
- Usage on gl.wikipedia.org
Metadata
This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.
Author | SRB |
---|---|
Width | 3,000 px |
Height | 1,941 px |
Compression scheme | Uncompressed |
Pixel composition | RGB |
Image data location | 26,538 |
Orientation | Normal |
Number of components | 3 |
Number of rows per strip | 1,941 |
Bytes per compressed strip | 34,938,000 |
Horizontal resolution | 600 dpi |
Vertical resolution | 600 dpi |
Data arrangement | chunky format |
Software used | Adobe Photoshop CS3 Windows |
File change date and time | 02:49, 12 December 2010 |
Color space | sRGB |
warning | unknown field with tag 37724 (0x935c) encountered. |