File:NLC416-08jh016233-9607 磺醯胺類之研究及製造法.pdf

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磺醯胺類之研究及製造法   (Wikidata search (Cirrus search) Wikidata query (SPARQL)  Create new Wikidata item based on this file)
Author
王世椿 吳蔚合著
image of artwork listed in title parameter on this page
Title
磺醯胺類之研究及製造法
Publisher
中國科學圖書儀器公司[發行者]
Description

目錄
第一章 磺酰胺化合物的歷史概述
第二章 磺酰胺類之分類
一 磺酰胺
二 磺酰胺的偶氮衍化物
三 n1　被代替之衍化物
四 n4　被代替之衍化物
五 marfanil
六 diphenylsulfone
第三章 磺酰胺噻唑之合成法
一 2-aminothiazole
二 p-acetaminobenzenesulfonyl chloride
三 p-acetaminobenzenesulfonamidothiazole
四 sulfathiazole
五 用有機溶劑製造 sulfathiazole
（1） 縮合
（2） 縮合物之精製
（3） 加水分解
六 用水為縮合溶劑之工業製造法
（1） 原料之支配
（2） p-acetaminobenzenesulfonyl chloride 之製造
（3） amino-thiazole 溶液之製備
（4） 縮合
（5） 縮合物之精製
（6） 加水分解
（7） 精製及脫色
（8） 製造時應加注意之事件
（9） 原料之選擇
第四章 磺酰胺及其衍化物之合成法
一 磺酰胺
（1） p-acetaminobenzenesulfonamide
（2） sulfamide
二 prontosil
三 sulfapyridin
（1） 2-aminopyridin 之製法
（2） sulfapyridin 之製法
四 sulfanilacetamide
五 sulfamethylthiazole
（1） 2-amino-4-methyl thiazole 之製法
（2） sulfamethyl thiazole 之合成
六 sulfaguaidin
（1） guanidin nitrate 之製備
（1） n4-acetylsulfanilyl guanidin 之製造
（1） sulfaguanidin
七 sulfadiazine
（1） isocytosine
（2） 2-amino-4-chloropyrimidin
（3） 2-amino-pyrimidin
（4） n4-acetylsulfanilylpyrimidin
（5） sulfadiazine
八 diseptal a
（1） n′-dimethyl sulfanilamide 之製造
（2） diseptal a 之合成
九 diseptal b 及 c
十 p-aminobenzenesulfon 3′,5′-dibromanilide
（1） 4-acetylaminobenzenesulfon 3′, 5′-dibrom 4′-aminoanilide
（2） 4-acetylamino benzenesulfon-3′, 5′-dibromanilide
（3） 4-amino-benzene sulfon 3′, 5′-dibrom anilide
十一 n4-acetylsulfanilamide
十二 n4-nicotinylsulfanilamide
（1） 自 sulfanilamide 與 nicotinyl chloride 合成
（2） 自氯磺酸與 nicotinylanilide 合成
第五章 水溶性磺酰胺類化合物之製造法
一 分類
二 prontosil soluble
（1） 2-naphthyl amine 3,6,8-trisulfonic acid
（2） 2-amino-8 hydroxy-naphthalene, 3,6-disulfonic acid
（3） 2-acetamino-8-hydroxy-naphthalene, 3,6-disulfonic acid
（4） diazo 溶液之調製
（5） prontosil soluble
三 磺酰胺類化合物之鈉鹽之製法
（1） sulfathiazole 鈉鹽之製法
（2） sulfadiazine 鈉鹽之製法
四 與 aldehyde sodium bisulfite 化合而成之水溶性化合物之製造法
（1） sodium p-sulfonamidphenylamino methane sulfonate
（2） sodium-p-sulfonamide-phenyl amino-benzylulfonate
（3） disodium (phenyl-propyl-amino-p-phenyl-sulfonamido-thiazole) disulfonate
第六章 與磺酰胺類構造及治療功效相似之化合物之合成法
一 diacetylamino-diphenyl sulfone
（1） 4-nitro-4′-amino-diphenyl sulfide
（2） 4,4′-diamino-diphenyl sulfide
（3） 4,4′-diacetylamino-diphenyl sulfide
（4） 4,4′-diacetyl-amino-diphenyl sulfone
二 4,4′diamino-diphenyl sulfone
三 4-amino-4′-nicotinyl amino-diphenyl sulfone
（1） 4-nitro-4′-nicotinylamino-diphenyl sulfide
（2） 4-nitro-4′-nicotinyl amino-diphenyl sulfone
（3） 4-amino-4′-nicotinyl amino-diphenyl sulfone
四 4,4′ diamino-diphenyl sulfone 之 glucose 及 glucose sodium bisulfite 之衍化物
五 4-amino-3′, 5′-dibromo-diphenvl sulfone
（1） 4-nitro-4′-acetylamino-diphenyl sulfide
（2） 4-nitro-4′-acetylamino-diphenyl sulfone
（3） 4-nitro-4′-amino-diphenyl sulfone
（4） 4-nitro-4′-amino 3′, 5′-dibromo-diphenyl sulfone
（5） 4-nitro-3′, 5′-dibromo-diphenyl-sulfone
（6） 4-amino-3′, 5′-dibromo-diphenyl sulfone
第七章 磺酰胺及其衍化物之定性及定量分析法
一 sulfanilamide
二 sulfapyridine
三 sulfapyridine 之鈉鹽
四 prontosil
五 sulfathiazole
六 sulfanilacetamide
第八章 磺酰胺類化合物之藥理
一 治療之原理
二 治療之範圍
三 吸收及排泄
四 副作用和毒性
（1） 對於消化器之障礙
（2） 對於赤血球之作用
（3） 溶血性貧血
（4） 白血球減少
（5） 對於皮膚之副作用
（6） 對於神經系統之副作用
（7） 對於泌尿器系統之副作用
（8） 全身症狀
五 磺酰胺類化合物各論
（1） próntosil
（2） prontosil soluble
（3） sulfamide
（4） diseptal a,b,c
（5） sulfanilacetamide
（6） sulfapyridine
（7） sulfathiazole
（8） sulfadiazine
（9） sulfaguanidine
（10） diamino diphenyl sulfone
（11） sulfanil-3′, 5′-dibromoanilide
第九章 潘納西林（penicillin） 之製造及其功用
附錄
marfanil 之卓效
關於penicillin

Language Chinese
Publication date 民國36[1947]
Source
institution QS:P195,Q732353
(民國時期文獻 民國圖書)
主題
InfoField
藥物:磺胺醋酰
中圖分類
InfoField
TQ468.1
載體形態
InfoField
105頁

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