File:Multiscale-Mechano-Biological-Finite-Element-Modelling-of-Oncoplastic-Breast-Surgery—Numerical-pone.0159766.s012.ogv

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Original file ‎(Ogg Theora video file, length 6.1 s, 1,104 × 791 pixels, 3.33 Mbps, file size: 2.42 MB)

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English: Wound Healing Simulation for Patient Case P-4 : Cell Density. The volume rendering represents the (normalised dimensionless) cell density, η/η0, in the wounded region. At the early stages of the simulation—similarly to S2 Video—cells (i.e. fibroblasts) are migrating and proliferating towards the wound, while mitosis of cells (e.g. myofibroblasts, etc.) is also supported by the newly formed vascular network in this region. Evidently, one month after BCT, an established extracellular matrix is formed, tissue granulation nearly completes and the breast tissue start to remodel and mature, hence, the decreasing rate of deformation at the operated breast. For explanation of the two-dimensional plot, see the description in S1 Video.
Date
Source S3 Video from Vavourakis V, Eiben B, Hipwell J, Williams N, Keshtgar M, Hawkes D (2016). "Multiscale Mechano-Biological Finite Element Modelling of Oncoplastic Breast Surgery—Numerical Study towards Surgical Planning and Cosmetic Outcome Prediction". PLOS ONE. DOI:10.1371/journal.pone.0159766. PMID 27466815. PMC: 4965022.
Author Vavourakis V, Eiben B, Hipwell J, Williams N, Keshtgar M, Hawkes D
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This file was transferred to Wikimedia Commons from PubMed Central by way of the Open Access Media Importer.
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Date/TimeThumbnailDimensionsUserComment
current20:32, 26 August 20166.1 s, 1,104 × 791 (2.42 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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