File:Identification-of-Injury-Specific-Proteins-in-a-Cell-Culture-Model-of-Traumatic-Brain-Injury-pone.0055983.s007.ogv

English: Uninjured cell cultures display less proliferation and no directional migration. Neurons, recognized by their round to oval somal shape and their extending axon and dendrites, migrate aimlessly and less fervently in uninjured cultures than injured ones. Although, proliferation is observed also in uninjured cultures (likely due to the relative immaturity of the neurons) less cell divisions are observed in uninjured cultures compared to injured ones. The astrocytes are recognized by their round cell nuclei and often highly vacuolized appearance and are frequently covered in dead cells and debris. In uninjured cultures, astrocytes are mostly concerned with clearing up the cellular debris and do not actively migrate or proliferate. No oligodendrocyte migration or proliferation was detected. Films are composed at 7 frames per second with images taken every 10 minutes for 24 h.