File:High-Affinity-Antigen-Recognition-of-the-Dual-Specific-Variants-of-Herceptin-Is-Entropy-Driven-in-pone.0017887.s001.ogv

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High-Affinity-Antigen-Recognition-of-the-Dual-Specific-Variants-of-Herceptin-Is-Entropy-Driven-in-pone.0017887.s001.ogv ‎(Ogg Theora video file, length 7.4 s, 640 × 480 pixels, 467 kbps, file size: 424 KB)

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English: Movie modeling the molecular acrobatics of CDRs for bH1 dual interaction. The significant structural plasticity of bH1 is highlighted by morphing between VEGF-bound bH1 (PDB code 3BDY) and HER2-bound bH1 (PDB code 3BE1) presented as described in Figure S1. Please note the highly distinct conformation of CDR-L1, the adjustment of the side chains of highlighted residues, and the side chains of LC-I30c and LC-Y32 that alternatively occupy the nearby cavity in HER2 bound bH1 or VEGF bound bH1, respectively. The movie (see movie S1) has been generated using the morphing function of Rigimol which is part of MacPymol 1.3 (www.pymol.org).
Date
Source Movie S1 from Bostrom J, Haber L, Koenig P, Kelley R, Fuh G (2011). "High Affinity Antigen Recognition of the Dual Specific Variants of Herceptin Is Entropy-Driven in Spite of Structural Plasticity". PLOS ONE. DOI:10.1371/journal.pone.0017887. PMID 21526167. PMC: 3081289.
Author Bostrom J, Haber L, Koenig P, Kelley R, Fuh G
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current02:52, 14 November 20127.4 s, 640 × 480 (424 KB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 480P 195 kbps Completed 16:59, 28 August 2018 3.0 s
Streaming 480p (VP9) 196 kbps Completed 11:37, 17 March 2024 1.0 s
VP9 360P 107 kbps Completed 16:58, 28 August 2018 3.0 s
Streaming 360p (VP9) Not ready Unknown status
VP9 240P 64 kbps Completed 16:58, 28 August 2018 3.0 s
Streaming 240p (VP9) 65 kbps Completed 00:01, 2 January 2024 0.0 s
WebM 360P 201 kbps Completed 23:40, 15 November 2012 3.0 s
Streaming 144p (MJPEG) 1.13 Mbps Completed 16:58, 14 November 2023 1.0 s

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