File:Growth-Cone-MKK7-mRNA-Targeting-Regulates-MAP1b-Dependent-Microtubule-Bundling-to-Control-Neurite-pbio.1001439.s028.ogv
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[edit]DescriptionGrowth-Cone-MKK7-mRNA-Targeting-Regulates-MAP1b-Dependent-Microtubule-Bundling-to-Control-Neurite-pbio.1001439.s028.ogv |
English: MKK7 KN rescue experiment II. Neurite extension dynamics of differentiating N1E-115 cells transfected with: (1) control siRNA and GFP; (2) MKK7 siRNA and GFP-MKK7/3′-UTR1; or (3) MKK7 siRNA and GFP-MKK7/3′-UTR2. Phase contrast time-lapse imaging and GFP fluorescence signal in ibw contrast are shown. GFP channel was acquired every fifth frame. Timescale is in hours∶minutes. Scale bar: 50 µm. Note robust rescue of neurite elongation with the GFP-MKK7/3′-UTR1 and GFP-MKK7/3′-UTR2 constructs. Also note highly unstable neurite extension in GFP-negative cells. |
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Source | Video S6 from Feltrin D, Fusco L, Witte H, Moretti F, Martin K, Letzelter M, Fluri E, Scheiffele P, Pertz O (2012). "Growth Cone MKK7 mRNA Targeting Regulates MAP1b-Dependent Microtubule Bundling to Control Neurite Elongation". PLOS Biology. DOI:10.1371/journal.pbio.1001439. PMID 23226105. PMC: 3514283. | ||
Author | Feltrin D, Fusco L, Witte H, Moretti F, Martin K, Letzelter M, Fluri E, Scheiffele P, Pertz O | ||
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current | 23:40, 15 December 2012 | 18 s, 420 × 630 (2.27 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Feltrin D, Fusco L, Witte H, Moretti F, Martin K, Letzelter M, Fluri E, Scheiffele P, Pertz O |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2012-12 |