File:Functional-Rotation-of-the-Transporter-AcrB-Insights-into-Drug-Extrusion-from-Simulations-pcbi.1000806.s011.ogv

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Original file(Ogg Theora video file, length 50 s, 1,314 × 802 pixels, 1.41 Mbps, file size: 8.4 MB)

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English: Movement of doxorubicin and of the four subdomains PC1, PC2, PN1, PN2 extracted from one TMD simulation along the T→O transition. Firstly the whole trimer is shown, then zoom is performed on the T monomer, in the region around the drug. Doxorubicin is shown initially in blue, and becomes red following the TMD time. Some residues of the binding pocket are also highlighted.
Date
Source Video S1 from Schulz R, Vargiu A, Collu F, Kleinekathöfer U, Ruggerone P (2010). "Functional Rotation of the Transporter AcrB: Insights into Drug Extrusion from Simulations". PLOS Computational Biology. DOI:10.1371/journal.pcbi.1000806. PMID 20548943. PMC: 2883587.
Author Schulz R, Vargiu A, Collu F, Kleinekathöfer U, Ruggerone P
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This file was published in a Public Library of Science journal. Their website states that the content of all PLOS journals is published under the Creative Commons Attribution 4.0 license (or its previous version depending on the publication date), unless indicated otherwise.
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Date/TimeThumbnailDimensionsUserComment
current18:32, 16 November 201250 s, 1,314 × 802 (8.4 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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VP9 720P 758 kbps Completed 08:00, 27 August 2018 44 s
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Streaming 144p (MJPEG) 509 kbps Completed 08:31, 13 November 2023 2.0 s

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