File:Estimating-Dose-Painting-Effects-in-Radiotherapy-A-Mathematical-Model-pone.0089380.s010.ogv

English: Time evolution of a heterogeneous tumor growth (where CCs and CSCs are present) for the high migration case with and CSC cycle duration equal to 48 h. Tumor growth is allowed unchecked from a size of about 105 cells until about 106 cells are present. Then, a homogeneous radiation therapy consisting of 2.52 Gy in the tumor is delivered. Treatment sessions are scheduled 7 days a week separated by 24 hours intervals along 30 sessions (without weekend interruptions). Depicted in dark and light green (respectively, dark and light red) are proliferating and quiescent CCs (respectively, proliferating and quiescent CSCs). Dead cells are represented in black. See Figure 10 (D) in the article.