File:Dynamic-3D-Cell-Rearrangements-Guided-by-a-Fibronectin-Matrix-Underlie-Somitogenesis-pone.0007429.s005.ogv

English: Multiphoton 4D image sequence of GFP expressing-cells in chick embryo PSM showing cell movements during somite formation. First segment of the video shows a portion of the PSM of a chick embryo (rostral is upwards, medial is to the left). In the beginning only one somite is formed, but at the end of 6 hours four new somites have formed. After zooming into a single somite the details of individual cell movements are shown. Several different morphogenetic stereotypical movements are identified in cells with different colors. Blue represents elongation of a medial cell, red cell accretion in the rostral and caudal walls, green egression, and yellow mesenchymal elongation and intercalation in the lateral wall. In the end, a zoom of a forming intersomitic cleft shows the continuous extension and retraction of pseudopodia. For more details refer to Figure 2 of the manuscript.