File:Development-of-a-macromolecular-prodrug-for-the-treatment-of-inflammatory-arthritis-mechanisms-ar3130-S1.ogv
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Size of this JPG preview of this OGG file: 572 × 600 pixels. Other resolutions: 229 × 240 pixels | 458 × 480 pixels | 992 × 1,040 pixels.
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DescriptionDevelopment-of-a-macromolecular-prodrug-for-the-treatment-of-inflammatory-arthritis-mechanisms-ar3130-S1.ogv |
English: Severe vasculature leakage associated with adjuvant-induced arthritis (AA) rat joint. A movie demonstrating the tissue transfer constant (Ki) (color) of the HPMA copolymer conjugate labeled with DOTA-Gd3+ (P-DOTA-Gd3+) in a representative AA rat right-hind limb, superimposed with a maximum intensity projection (MIP) image (black and white) of the same limb. The inserted color bar represents the color code for Ki values in the map from 0 to 0.005/min. Higher vascular leakage was found to be associated with the soft tissue around the distal tibia. |
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Date | |||
Source | Quan L, Purdue P, Liu X, Boska M, Lele S, Thiele G, Mikuls T, Dou H, Goldring S, Wang D (2010). "Development of a macromolecular prodrug for the treatment of inflammatory arthritis: mechanisms involved in arthrotropism and sustained therapeutic efficacy". Arthritis Research & Therapy. DOI:10.1186/ar3130. PMID 20836843. PMC: 2990997. | ||
Author | Quan L, Purdue P, Liu X, Boska M, Lele S, Thiele G, Mikuls T, Dou H, Goldring S, Wang D | ||
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This file is licensed under the Creative Commons Attribution 2.0 Generic license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 21:26, 18 November 2012 | 8.3 s, 992 × 1,040 (689 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Short title | Additional file 1 |
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Author | Quan L, Purdue P, Liu X, Boska M, Lele S, Thiele G, Mikuls T, Dou H, Goldring S, Wang D |
Usage terms | http://creativecommons.org/licenses/by/2.0/ |
Image title | Severe vasculature leakage associated with adjuvant-induced arthritis (AA) rat joint. A movie demonstrating the tissue transfer constant (Ki) (color) of the HPMA copolymer conjugate labeled with DOTA-Gd3+ (P-DOTA-Gd3+) in a representative AA rat right-hind limb, superimposed with a maximum intensity projection (MIP) image (black and white) of the same limb. The inserted color bar represents the color code for Ki values in the map from 0 to 0.005/min. Higher vascular leakage was found to be associated with the soft tissue around the distal tibia. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2010 |
Categories:
- Immunologic adjuvants
- Antirheumatic agents
- Experimental arthritis
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- Fibroblasts
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