File:An-Excitatory-Loop-with-Astrocytes-Contributes-to-Drive-Neurons-to-Seizure-Threshold-pbio.1000352.s008.ogv

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An-Excitatory-Loop-with-Astrocytes-Contributes-to-Drive-Neurons-to-Seizure-Threshold-pbio.1000352.s008.ogv ‎(Ogg Theora video file, length 26 s, 198 × 254 pixels, 787 kbps, file size: 2.44 MB)

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English: Response of astrocytes to ictal and interictal discharges in EC slices. This video shows the synchronous Ca2+ increase in EC neurons after slice perfusion with picrotoxin/zero-Mg2+ that reflects an interictal and an ictal discharge (as reported in Figure 1A and 1B). Note that at the beginning of the video there is an interictal discharge that activates only one astrocyte. A subsequent ictal discharge evokes a large and synchronous Ca2+ response in most astrocytes (indicated by the arrowheads in the first frame). In the final part of the video, synchronous, repetitive Ca2+ elevations in neurons reflect the afterdischarges typical of the late ictal phase. Time frame, 314 ms.
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Source Video S1 from Gómez-Gonzalo M, Losi G, Chiavegato A, Zonta M, Cammarota M, Brondi M, Vetri F, Uva L, Pozzan T, de Curtis M, Ratto G, Carmignoto G (2010). "An Excitatory Loop with Astrocytes Contributes to Drive Neurons to Seizure Threshold". PLOS Biology. DOI:10.1371/journal.pbio.1000352. PMID 20405049. PMC: 2854117.
Author Gómez-Gonzalo M, Losi G, Chiavegato A, Zonta M, Cammarota M, Brondi M, Vetri F, Uva L, Pozzan T, de Curtis M, Ratto G, Carmignoto G
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Date/TimeThumbnailDimensionsUserComment
current16:25, 16 November 201226 s, 198 × 254 (2.44 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 240P 205 kbps Completed 11:04, 17 August 2018 21 s
Streaming 240p (VP9) 205 kbps Completed 02:15, 12 December 2023 1.0 s
WebM 360P 313 kbps Completed 16:51, 16 November 2023 2.0 s
Streaming 144p (MJPEG) 576 kbps Completed 05:22, 30 October 2023 1.0 s

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