File:ATX-2-the-C.-elegans-Ortholog-of-Human-Ataxin-2-Regulates-Centrosome-Size-and-Microtubule-Dynamics-pgen.1006370.s009.ogv

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Original file ‎(Ogg Theora video file, length 3.0 s, 834 × 294 pixels, 502 kbps, file size: 184 KB)

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English: The atx-2 mutant embryo fails to extrude polar bodies, resulting in extra DNA. Control and atx-2(RNAi) embryos expressing GFP-α-Tubulin, mCherry-γ-Tubulin and mCherry-H2B. While the control embryo displays successful polar body extrusion, in the atx-2(RNAi) embryo the extrusion of the second polar body fails (arrow at t = 12), leading to extra DNA associated with the maternal pronucleus. Note cell cycle delay and the orientation of meiotic spindle in the atx-2(RNAi) embryo—the meiotic spindle aligns 90° to the cell cortex throughout the meiosis II. However, in the control embryo the meiotic spindle aligns parallel to the cortex until anaphase and rotates 90° just before polar extrusion [74]. Each frame is equal to 1 min of elapsed time (t = 0 at metaphase of meiosis II; 5 fps). Bar, 5 μm.
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Source S3 Movie from Stubenvoll M, Medley J, Irwin M, Song M (2016). "ATX-2, the C. elegans Ortholog of Human Ataxin-2, Regulates Centrosome Size and Microtubule Dynamics". PLOS Genetics. DOI:10.1371/journal.pgen.1006370. PMID 27689799. PMC: 5045193.
Author Stubenvoll M, Medley J, Irwin M, Song M
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Date/TimeThumbnailDimensionsUserComment
current05:40, 29 October 20163.0 s, 834 × 294 (184 KB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 360P 64 kbps Completed 04:51, 16 August 2018 2.0 s
Streaming 360p (VP9) 65 kbps Completed 21:43, 17 December 2023 0.0 s
VP9 240P 35 kbps Completed 04:51, 16 August 2018 1.0 s
Streaming 240p (VP9) 37 kbps Completed 09:27, 9 December 2023 1.0 s
WebM 360P 408 kbps Completed 05:40, 29 October 2016 2.0 s
Streaming 144p (MJPEG) 149 kbps Completed 13:36, 29 October 2023 1.0 s

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