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1 00:00:00,000 --> 00:00:07,000 Human immunodeficiency virus infection (or HIV), and acquired immune deficiency syndrome (or AIDS), 2 00:00:07,100 --> 00:00:12,204 is a spectrum of conditions caused by infection with the human immunodeficiency virus.[1][2][3] 3 00:00:12,304 --> 00:00:17,071 Following the initial infection, a person may not notice any symptoms, 4 00:00:17,171 --> 00:00:20,500 or may experience a brief period of flu-like illness.[4] 5 00:00:20,600 --> 00:00:24,071 This is followed by a prolonged period with no symptoms.[5] 6 00:00:24,171 --> 00:00:29,018 As the infection progresses, it interferes more with the immune system, 7 00:00:29,018 --> 00:00:33,250 increasing the risk of developing common infections such as tuberculosis, 8 00:00:33,350 --> 00:00:35,700 as well as other opportunistic infections, 9 00:00:35,800 --> 00:00:40,018 and tumors that rarely affect people who have uncompromised immune systems.[4] 10 00:00:40,118 --> 00:00:46,500 These late symptoms of infection, are referred to as acquired immunodeficiency syndrome (or AIDS).[5] 11 00:00:46,600 --> 00:00:50,709 This stage is also associated with unintended weight loss.[5] 12 00:00:50,709 --> 00:00:56,900 HIV is spread primarily by unprotected sex (including anal, and oral sex), 13 00:00:57,000 --> 00:01:00,900 contaminated blood transfusions, and hypodermic needles. 14 00:01:01,000 --> 00:01:04,900 It can also be spread from mother to child during pregnancy, 15 00:01:05,000 --> 00:01:06,900 delivery, or breastfeeding.[6] 16 00:01:07,000 --> 00:01:12,873 Some bodily fluids, such as saliva and tears, do not transmit HIV.[7] 17 00:01:12,873 --> 00:01:18,280 Methods of prevention include safe sex, needle exchange programs, 18 00:01:18,380 --> 00:01:23,000 treating those who are infected, pre, and post exposure prophylaxis, 19 00:01:23,100 --> 00:01:24,280 and male circumcision.[4] 20 00:01:24,380 --> 00:01:28,500 The spread of HIV from mother to child, during childbirth, 21 00:01:28,600 --> 00:01:32,624 can be prevented by giving both of them antiretroviral medication.[4] 22 00:01:32,624 --> 00:01:34,500 There is no cure or vaccine; 23 00:01:34,600 --> 00:01:39,128 however, antiretroviral treatment can slow the course of the disease, 24 00:01:39,228 --> 00:01:42,028 and may lead to a near-normal life expectancy.[5][8] 25 00:01:42,128 --> 00:01:46,112 Treatment is recommended as soon as the diagnosis is made.[9] 26 00:01:46,212 --> 00:01:51,312 Without treatment, the average survival time after infection is 11 years.[10] 27 00:01:51,412 --> 00:01:58,012 In 2016, about 36.7 million people were living with HIV, 28 00:01:58,112 --> 00:02:00,600 and it resulted in 1 million deaths.[11] 29 00:02:00,700 --> 00:02:06,900 There were 300,000 fewer new HIV cases in 2016 than in 2015.[12] 30 00:02:07,000 --> 00:02:11,531 Most of those infected, live in sub-Saharan Africa.[4] 31 00:02:11,631 --> 00:02:16,900 From the time AIDS was identified in the early 1980s, to 2017, 32 00:02:17,000 --> 00:02:21,142 the disease has caused an estimated 35 million deaths worldwide.[13] 33 00:02:21,142 --> 00:02:24,401 HIV AIDS is considered a pandemic, 34 00:02:24,501 --> 00:02:27,701 because it is a disease outbreak which is present over a large area, 35 00:02:27,801 --> 00:02:29,501 and is actively spreading.[14] 36 00:02:30,301 --> 00:02:34,585 HIV originated in west-central Africa during the late 19th, 37 00:02:34,685 --> 00:02:38,085 or early 20th century during colonialism.[15] 38 00:02:38,185 --> 00:02:44,889 AIDS was first recognized by the United States Centers for Disease Control and Prevention in 1981, 39 00:02:44,989 --> 00:02:49,089 and the HIV virus was identified as its cause shortly after.[16] 40 00:02:49,089 --> 00:02:52,840 HIV-AIDS has had a large impact on society, 41 00:02:52,940 --> 00:02:55,940 both as an illness and as a source of discrimination.[17] 42 00:02:56,040 --> 00:02:59,900 The disease also has large economic impacts.[17] 43 00:03:00,000 --> 00:03:02,900 There are many misconceptions about HIV-AIDS, 44 00:03:03,000 --> 00:03:08,071 such as the belief that it can be transmitted by casual, non-sexual contact.[18] 45 00:03:08,171 --> 00:03:12,900 The disease has become subject to many controversies involving religion, 46 00:03:13,000 --> 00:03:17,155 including the Catholic Church's position not to support condom use as prevention.[19] 47 00:03:17,255 --> 00:03:22,900 Despite this, HIV-AIDS has attracted international medical and political attention, 48 00:03:23,000 --> 00:03:27,654 as well as large-scale funding since it was identified in the 1980s.[20]