File:Tracking-the-Luminal-Exposure-and-Lymphatic-Drainage-Pathways-of-Intravaginal-and-Intrarectal-pone.0092830.s003.ogv
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[edit]DescriptionTracking-the-Luminal-Exposure-and-Lymphatic-Drainage-Pathways-of-Intravaginal-and-Intrarectal-pone.0092830.s003.ogv |
English: Maximum intensity projections representing a 3D reconstruction of magnetic resonance imaging to visualize contrast dye introduced intrarectally in a rhesus macaque exposed to a 3 ml inoculum. Gadofoveset trisodium contrast dye was administered intrarectally and 20 minutes later animals were returned to a recumbent position and MRI was performed. The 3 ml exposure shown here shows robust inoculum penetration including within the distal descending colon. Bladder compression of the distal descending colon results in a thin layer of dye between these two sites, which, though difficult to see, likely coats the compressed mucosa. Although background contrast was detected in the small intestines due to animal diet, contrast dye in the rectum and descending colon is clearly visible. This movie was selected to represent the 2 animals tested by MRI for luminal coverage following a 3 ml exposure. |
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Source | Movie S2 from Smedley J, Turkbey B, Bernardo M, Del Prete G, Estes J, Griffiths G, Kobayashi H, Choyke P, Lifson J, Keele B (2014). "Tracking the Luminal Exposure and Lymphatic Drainage Pathways of Intravaginal and Intrarectal Inocula Used in Nonhuman Primate Models of HIV Transmission". PLOS ONE. DOI:10.1371/journal.pone.0092830. PMID 24667371. PMC: 3965472. | |||
Author | Smedley J, Turkbey B, Bernardo M, Del Prete G, Estes J, Griffiths G, Kobayashi H, Choyke P, Lifson J, Keele B | |||
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current | 23:18, 10 December 2014 | 30 s, 768 × 768 (1.25 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Smedley J, Turkbey B, Bernardo M, Del Prete G, Estes J, Griffiths G, Kobayashi H, Choyke P, Lifson J, Keele B |
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Usage terms | http://creativecommons.org/publicdomain/zero/1.0/ |
Image title | Maximum intensity projections representing a 3D reconstruction of magnetic resonance imaging to visualize contrast dye introduced intrarectally in a rhesus macaque exposed to a 3 ml inoculum. Gadofoveset trisodium contrast dye was administered intrarectally and 20 minutes later animals were returned to a recumbent position and MRI was performed. The 3 ml exposure shown here shows robust inoculum penetration including within the distal descending colon. Bladder compression of the distal descending colon results in a thin layer of dye between these two sites, which, though difficult to see, likely coats the compressed mucosa. Although background contrast was detected in the small intestines due to animal diet, contrast dye in the rectum and descending colon is clearly visible. This movie was selected to represent the 2 animals tested by MRI for luminal coverage following a 3 ml exposure. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2014 |