File:The adult ovary possesses an extensive lymphatic network.png

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Figure 5. The adult ovary possesses an extensive lymphatic network. A–C)

In the ovarian cortex, secondary follicles (encircled) with DDX4-positive oocytes are devoid of Prox1-EGFP positive lymphatic vessels, but lymphatic vessels are readily observed in close proximity. D–F) The ovarian medulla visualized by staining of the theca cell marker CYP11A1, contains a rich network of lymphatic vessels. G–I) The granulosa layer of secondary follicles localized by FOXL2-staining is devoid of lymphatic vessels, but with Prox1-EGFP positive vessels localizing very close to the border between the theca and granulosa layers (dotted circle). Oocytes of primary follicles containing a single layer of FOXL2-positive granulosa cells express a discernable level of Prox1-EGFP (arrow). Scale bar A = 100 µm.

https://doi.org/10.1371/journal.pone.0052620.g005
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Source https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052620 Svingen T, François M, Wilhelm D, Koopman P (2012) Three-Dimensional Imaging of Prox1-EGFP Transgenic Mouse Gonads Reveals Divergent Modes of Lymphangiogenesis in the Testis and Ovary. PLoS ONE 7(12): e52620. https://doi.org/10.1371/journal.pone.0052620
Author Lim J, Maher GJ, Turner GDH, Dudka-Ruszkowska W, Taylor S, Meyts ER-D, et al.

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© 2012 Svingen et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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current20:26, 2 August 2024Thumbnail for version as of 20:26, 2 August 20243,439 × 2,968 (14.27 MB)Rasbak (talk | contribs){{Information |description=Figure 5. The adult ovary possesses an extensive lymphatic network. A–C) In the ovarian cortex, secondary follicles (encircled) with DDX4-positive oocytes are devoid of Prox1-EGFP positive lymphatic vessels, but lymphatic vessels are readily observed in close proximity. D–F) The ovarian medulla visualized by staining of the theca cell marker CYP11A1, contains a rich network of lymphatic vessels. G–I) The granulosa layer of secondary follicles localized by FOXL2-sta...

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