File:The Diagnostic value of Ro(SS-A) and La(SS-B) antibodies for patients with systemic lupus Erythematosus (SLE).pdf

From Wikimedia Commons, the free media repository
Jump to navigation Jump to search
Go to page
next page →
next page →
next page →

Original file ‎(1,247 × 1,758 pixels, file size: 2.03 MB, MIME type: application/pdf, 39 pages)

Captions

Captions

The Diagnostic value of Ro(SS-A) and La(SS-B) antibodies for patients with systemic lupus Erythematosus (SLE)

Summary

[edit]
Description
English: The Diagnostic Value ofRo (SS-A) and La (SS-B) Antibodies for Patients with Systemic Lupus Erythematosus (SLE). SLE is a chronic inflammatory disease of unknown cause that may affect the skin, joints, kidneys, lungs, nervous system, serous membranes and other organs of the body. The clinical course of SLE is characterized by periods of remission and chronic or acute relapses. Genetic and other (e.g., environmental) factors seem to plây' a role in its pathogenesis. In this study, serum Ro (SS-A) and La (SS-B) antibody levels were measured by ELISA test in patients with SLE. The relationship between specific clinical and laboratory findings of SLE and Ro (SS-A), La (SS-B) antibody positivity were investigated. Forty-four patients with SLE (39 females, 5 males) were introduced into this study and the mean age was 30 (rangel5 to 49) for the patients. If we regard 44 patients with SLE, Ro (SS-A) antibodies were measured as positive in 10 patients (22.73 %), La (SS-B) antibodies were measured as positive in 6 patients (13.64 %). After that, a correlation between specific clinical and laboratory findings of SLE and Ro (SS- A), La (SS-B) antibodies was investigated. However it was not found a significant relationship. In conclusion, if a significant relationship can be found in studies with the other antinuclear antibodies, this will be an important step to identify, follow, therapy, and prognosis of SLE. In other words, there is a need for other future studies to be made dealing with this subject.
Türkçe: SLE, sebebi bilinmeyen kronik inflamatuar bir hastalıktır. Deri, eklemler, böbrek, akciğerler, sinir sistemi, seröz membranlar ve diğer organları etkiler. SLE'nin klinik seyri remisyon periyotları ve akut veya kronik relapslar şeklindedir. Genetik ve diğer (çevresel) faktörler patogenezde rol aldığı düşünülmektedir. Bu çalışmada SLE'li hasta serumlarında Ro (S S- A) ve La (SS-B) antikorları ELISA testiyle bakıldı. SLE'nin spesifik klinik ve laboratuvar bulgularıyla Ro (S S- A) ve La (SS-B) antikor pozitifliği arasındaki ilişki araştırıldı. Çalışmaya katılan 44 SLE'li hastanın (39 kadın, 5 erkek) yaş ortalaması 30 (15-49) idi. Çalışmaya dahil edilen ANA pozitif 44 SLE'li -hastanın % 22.73'ünde (10 hasta) Ro (SS-A) pozitif ve % 13.64'ünde (6 hasta) La (SS-B) antikoru pozitif olarak saptandı. Daha sonra SLE'li hastalardaki spesifik klinik ve laboratuvar bulgularla Ro (SS-A) ve La(SS-B) antikorları arasında korelasyon araştırıldı. Ancak anlamlı bir ilişki saptanamadı. Sonuç olarak, diğer antinükleer antikor tipleriyle yapılacak çalışmalarda anlamlı bir ilişkinin varlığı gösterilebilirse SLE'nin teşhis, takip, tedavi ve prognozunun belirlenmesinde önemli bir adım atılmış olacaktır. Yani bu konuda yapılacak daha ilerki çalışmalara ihtiyaç duyulmaktadır.
Date
Source Own work
Author Tkimilli

Gulhane Military Medical Faculty,Internal Medicine Department,Ankara,Turkey

Licensing

[edit]
I, the copyright holder of this work, hereby publish it under the following license:
w:en:Creative Commons
attribution share alike
This file is licensed under the Creative Commons Attribution-Share Alike 4.0 International license.
You are free:
  • to share – to copy, distribute and transmit the work
  • to remix – to adapt the work
Under the following conditions:
  • attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use.
  • share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.

File history

Click on a date/time to view the file as it appeared at that time.

Date/TimeThumbnailDimensionsUserComment
current21:35, 9 June 2021Thumbnail for version as of 21:35, 9 June 20211,247 × 1,758, 39 pages (2.03 MB)Dr.Tuncay KIMILLI (talk | contribs)Uploaded own work with UploadWizard

You cannot overwrite this file.

There are no pages that use this file.

Metadata

This file contains additional information such as Exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The timestamp is only as accurate as the clock in the camera, and it may be completely wrong.

Retrieved from "https://commons.wikimedia.org/w/index.php?title=File:The_Diagnostic_value_of_Ro(SS-A)_and_La(SS-B)_antibodies_for_patients_with_systemic_lupus_Erythematosus_(SLE).pdf&oldid=801674233"