File:Targeting-CD28-CTLA-4-and-PD-L1-Costimulation-Differentially-Controls-Immune-Synapses-and-Function-pone.0083139.s006.ogv
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Targeting-CD28-CTLA-4-and-PD-L1-Costimulation-Differentially-Controls-Immune-Synapses-and-Function-pone.0083139.s006.ogv (Ogg Theora video file, length 10 s, 129 × 96 pixels, 77 kbps, file size: 93 KB)
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[edit]DescriptionTargeting-CD28-CTLA-4-and-PD-L1-Costimulation-Differentially-Controls-Immune-Synapses-and-Function-pone.0083139.s006.ogv |
English: Addition of CTLA-4 antagonists to CD28 antagonists restores Teff–APC short contacts between Treg and APCs. Representative time-lapse video similar to Movie S4 (over 25 minutes), performed in the presence of 10 µg/ml FR104, an antagonist anti-CD28 antibody plus 10 µg/ml 147.1, an antagonist anti-CTLA-4 antibody. Treg (green) showed low levels of calcium flux. Contact-time, motility are shown in Fig. 3C, D, H, I and J. Calcium responses are shown in Fig. 4C and D. |
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Source | Movie S6 from Dilek N, Poirier N, Hulin P, Coulon F, Mary C, Ville S, Vie H, Clemenceau B, Blancho G, Vanhove B (2013). "Targeting CD28, CTLA-4 and PD-L1 Costimulation Differentially Controls Immune Synapses and Function of Human Regulatory and Conventional T-Cells". PLOS ONE. DOI:10.1371/journal.pone.0083139. PMC: 3871694. | ||
Author | Dilek N, Poirier N, Hulin P, Coulon F, Mary C, Ville S, Vie H, Clemenceau B, Blancho G, Vanhove B | ||
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 01:57, 31 December 2013 | 10 s, 129 × 96 (93 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Dilek N, Poirier N, Hulin P, Coulon F, Mary C, Ville S, Vie H, Clemenceau B, Blancho G, Vanhove B |
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Usage terms | http://creativecommons.org/licenses/by/4.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2013 |