File:TDP-43-Mediated-Neuron-Loss-In-Vivo-Requires-RNA-Binding-Activity-pone.0012247.s005.ogv
TDP-43-Mediated-Neuron-Loss-In-Vivo-Requires-RNA-Binding-Activity-pone.0012247.s005.ogv (Ogg multiplexed audio/video file, Theora/Vorbis, length 30 s, 352 × 288 pixels, 373 kbps overall, file size: 1.34 MB)
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[edit]DescriptionTDP-43-Mediated-Neuron-Loss-In-Vivo-Requires-RNA-Binding-Activity-pone.0012247.s005.ogv |
English: Abnormal locomotion and wing posture in aged TDP-43WT expressing flies. Example of a fly with pan-neural expression of TDP-43WT. Note the lateral “hanging wing” phenotype. Dependent on expression strength and time, TDP-43WT flies lost their ability to fly, had reduced escape behavior (even if pushed with a brush) and were not able to reach an upright position after being placed dorsal side down in a reasonable time. |
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Source | Video S1 from Voigt A, Herholz D, Fiesel F, Kaur K, Müller D, Karsten P, Weber S, Kahle P, Marquardt T, Schulz J (2010). "TDP-43-Mediated Neuron Loss In Vivo Requires RNA-Binding Activity". PLOS ONE. DOI:10.1371/journal.pone.0012247. PMID 20806063. PMC: 2923622. | ||
Author | Voigt A, Herholz D, Fiesel F, Kaur K, Müller D, Karsten P, Weber S, Kahle P, Marquardt T, Schulz J | ||
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current | 10:14, 31 October 2012 | 30 s, 352 × 288 (1.34 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Abnormal locomotion and wing posture in aged TDP-43WT expressing flies. Example of a fly with pan-neural expression of TDP-43WT. Note the lateral ?hanging wing? phenotype. Dependent on expression strength and time, TDP-43WT flies lost their ability to fly, had reduced escape behavior (even if pushed with a brush) and were not able to reach an upright position after being placed dorsal side down in a reasonable time. |
Software used | |
Date and time of digitizing | 2010 |
Language | English |
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