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English: Main metabolic pathways involved in hamartoma predisposition syndromes (PJS: Peutz-Jeghers syndrome; CS/BRRS - Cowden syndrome/Bannayan-Ruvalcaba-Riley syndrome; TSC - tuberous sclerosis complex. PI3K – phosphoinositol kinase, PIP3 – phosphatidylinositol-3,4,5-triphosphate; PIP2 – phosphatidylinositol-4,5-bisphosphate; PTEN - phosphatase and tensin homolog; TSC1 and TSC2 - hamartin/tuberin complex; mTOR - mammalian target of rapamycin. Therapeuthic potential of rapamycin and other inhibitors of mTOR signalling is presented
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own work, partially based on figure 3 from Zbuk KM, Eng C. Hamartomatous polyposis syndromes. Nat Clin Pract Gastroenterol Hepatol. 4, 9, 492-502. 2007. PMID 17768394. doi:10.1038/ncpgasthep0902

 
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Author Filip em
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Date/TimeThumbnailDimensionsUserComment
current23:23, 24 August 2008Thumbnail for version as of 23:23, 24 August 2008987 × 467 (170 KB)Filip em (talk | contribs){{Information |Description= |Source= |Date= |Author= |Permission= |other_versions= }}
08:53, 15 August 2008Thumbnail for version as of 08:53, 15 August 2008967 × 474 (120 KB)Filip em (talk | contribs){{Information |Description= |Source= |Date= |Author= |Permission= |other_versions= }}
23:54, 11 January 2008Thumbnail for version as of 23:54, 11 January 2008973 × 499 (95 KB)Filip em (talk | contribs)
13:29, 17 December 2007Thumbnail for version as of 13:29, 17 December 2007973 × 499 (91 KB)Filip em (talk | contribs){{Information |Description= |Source=own work, based on figure 3 from Zbuk KM, Eng C. Hamartomatous polyposis syndromes. Nat Clin Pract Gastroenterol Hepatol. 4, 9, 492-502. 2007. PMID 17768394. DOI:10.1038/ncpgasthep0902 |Date=17-12-2007 |Author= [[User:F

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