File:Spastic-Paraplegia-Mutation-N256S-in-the-Neuronal-Microtubule-Motor-KIF5A-Disrupts-Axonal-Transport-pgen.1003066.s013.ogv
Spastic-Paraplegia-Mutation-N256S-in-the-Neuronal-Microtubule-Motor-KIF5A-Disrupts-Axonal-Transport-pgen.1003066.s013.ogv (Ogg Theora video file, length 4.6 s, 500 × 114 pixels, 127 kbps, file size: 72 KB)
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[edit]DescriptionSpastic-Paraplegia-Mutation-N256S-in-the-Neuronal-Microtubule-Motor-KIF5A-Disrupts-Axonal-Transport-pgen.1003066.s013.ogv |
English: (Related to Figure 5.) In vivo imaging of mitochondrial transport in Khcwt+N262S larvae. In vivo imaging of axonal transport of mitochondria in Khcwt+N262S expressing larvae. Movie is shown at 15 fps. Mitochondria were visualized by D42>mito-GFP expression at 29°C. Flux but not velocity of mitochondria is strongly reduced both anterogradely and retrogradly when compared to w1118 and Khcwt expressing larvae. |
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Source | Video S7 from Füger P, Sreekumar V, Schüle R, Kern J, Stanchev D, Schneider C, Karle K, Daub K, Siegert V, Flötenmeyer M, Schwarz H, Schöls L, Rasse T (2012). "Spastic Paraplegia Mutation N256S in the Neuronal Microtubule Motor KIF5A Disrupts Axonal Transport in a Drosophila HSP Model". PLOS Genetics. DOI:10.1371/journal.pgen.1003066. PMID 23209432. PMC: 3510046. | ||
Author | Füger P, Sreekumar V, Schüle R, Kern J, Stanchev D, Schneider C, Karle K, Daub K, Siegert V, Flötenmeyer M, Schwarz H, Schöls L, Rasse T | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 22:16, 6 December 2012 | 4.6 s, 500 × 114 (72 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2012-11 |