File:Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle Ca2-TRLgDb5WKoA.webm
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[edit]DescriptionRapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle Ca2-TRLgDb5WKoA.webm |
English: The webinar "Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle-Ca2+ channel distances" was given by Susanne Ditlevsen, from the Department of Mathematical Sciences of the University of Copenhagen...In this presentation, she discusses that postulated facilitation mechanisms operating via activity-dependent changes of vesicular release probability (e.g. by a facilitation fusion sensor) generate too little facilitation and too much variance. In contrast, Ca2+-dependent mechanisms rapidly increasing the number of releasable vesicles reliably reproduce short-term plasticity and variance of synaptic responses. Susanne proposes activity-dependent inhibition of vesicle un-priming or release site activation as novel facilitation mechanisms...Find other details about this seminar and the others in the series here: .https://neuromat.numec.prp.usp.br/content/nmweb/ |
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Source | YouTube: Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle Ca2 – View/save archived versions on archive.org and archive.today |
Author | NeuroMat |
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[edit]This media was produced by NeuroMat and was licensed as Creative Commons BY-SA 4.0. The Research, Innovation and Dissemination Center for Neuromathematics (RIDC NeuroMat) is a Brazilian research center hosted by the University of São Paulo and funded by the São Paulo Research Foundation (FAPESP).
Attribution in English: RIDC NeuroMat Attribution in Portuguese: CEPID NeuroMat |
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current | 05:11, 26 October 2020 | 1 h 13 min 22 s, 1,280 × 720 (192.6 MB) | Carybe (talk | contribs) | =={{int:filedesc}}== {{Information |description={{pt|1=The webinar "Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle-Ca2+ channel distances" was given by Susanne Ditlevsen, from the Department of Mathematical Sciences of the University of Copenhagen...In this presentation, she discusses that postulated facilitation mechanisms operating via activity-dependent changes of vesicular release probability (e.g. by a facilitation fusion sensor) generat... |
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Short title | Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle Ca2 |
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Author | NeuroMat |
User comments | The webinar "Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle-Ca2+ channel distances" was given by Susanne Ditlevsen, from the Department of Mathematical Sciences of the University of Copenhagen.
In this presentation, she discusses that postulated facilitation mechanisms operating via activity-dependent changes of vesicular release probability (e.g. by a facilitation fusion sensor) generate too little facilitation and too much variance. In contrast, Ca2+-dependent mechanisms rapidly increasing the number of releasable vesicles reliably reproduce short-term plasticity and variance of synaptic responses. Susanne proposes activity-dependent inhibition of vesicle un-priming or release site activation as novel facilitation mechanisms. Find other details about this seminar and the others in the series here: https://neuromat.numec.prp.usp.br/content/nmweb/ |
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