File:Prion-Shedding-from-Olfactory-Neurons-into-Nasal-Secretions-ppat.1000837.s004.ogv
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[edit]DescriptionPrion-Shedding-from-Olfactory-Neurons-into-Nasal-Secretions-ppat.1000837.s004.ogv |
English: Video of a three-dimensional reconstruction of a dendritic knob following immunofluorescence staining for olfactory marker protein and PrP Sc in the olfactory sensory epithelium of a HY TME-infected hamster. Laser scanning confocal microscopy of olfactory marker protein (OMP)(red, top panel), PrP Sc (green, middle panel), and for both OMP and PrP Sc (bottom panel) in the same field of view was performed as described in Figure 4 . LSCM image stacks (0.10 µM optical slice) through the thickness of the tissue were used to generate a three-dimensional reconstruction of an individual dendritic knob. This movie illustrates a 360° stereoview of the dendritic knob (OMP immunofluorescence) and PrP Sc located within the dendritic knob of an olfactory receptor neuron.
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Source | Video S1 from Bessen R, Shearin H, Martinka S, Boharski R, Lowe D, Wilham J, Caughey B, Wiley J. "Prion Shedding from Olfactory Neurons into Nasal Secretions". PLOS Pathogens. DOI:10.1371/journal.ppat.1000837. PMID 20419120. PMC: 2855443. | ||
Author | Bessen R, Shearin H, Martinka S, Boharski R, Lowe D, Wilham J, Caughey B, Wiley J | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 11:55, 10 October 2012 | 6.4 s, 689 × 817 (483 KB) | Open Access Media Importer Bot (talk | contribs) | Uploaded with the Open Access Media Importer. (test edit) botrequest |
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Short title | Video S1 |
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Author | Bessen R, Shearin H, Martinka S, Boharski R, Lowe D, Wilham J, Caughey B, Wiley J |
Usage terms | http://creativecommons.org/publicdomain/zero/1.0/ |
Image title | |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2010-04-15 |
Categories:
- Videos of infections of central nervous system
- Videos of diseases due to prions
- Western blot
- Chordate brainstem
- Fluorescent antibody technique
- Confocal microscopic movies from Open Access Journals
- Nasal lavage
- Nasal lavage fluid
- Videos of neurons
- Chordate olfactory bulb
- Olfactory mucosa
- Nervus olfactorius
- PrPSc proteins