File:Plk1-Inhibition-Causes-Post-Mitotic-DNA-Damage-and-Senescence-in-a-Range-of-Human-Tumor-Cell-Lines-pone.0111060.s010.ogv

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Plk1-Inhibition-Causes-Post-Mitotic-DNA-Damage-and-Senescence-in-a-Range-of-Human-Tumor-Cell-Lines-pone.0111060.s010.ogv (Ogg Theora video file, length 32 s, 672 × 512 pixels, 2.37 Mbps, file size: 9.05 MB)

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English: HCT116 cells were treated with the PLK1 small molecule inhibitor BI 2536 (10 nM) and time lapsed video microscopy was used to visualize cells out to 5 days. The predominant outcome is a transient mitotic arrest, followed by an exit from mitosis (presumably through a mitotic slippage mechanism), followed in many cases by senescence.
Date
Source Movie S2 from Driscoll D, Chakravarty A, Bowman D, Shinde V, Lasky K, Shi J, Vos T, Stringer B, Amidon B, D'Amore N, Hyer M (2014). "Plk1 Inhibition Causes Post-Mitotic DNA Damage and Senescence in a Range of Human Tumor Cell Lines". PLOS ONE. DOI:10.1371/journal.pone.0111060. PMID 25365521. PMC: 4218841.
Author Driscoll D, Chakravarty A, Bowman D, Shinde V, Lasky K, Shi J, Vos T, Stringer B, Amidon B, D'Amore N, Hyer M
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Date/TimeThumbnailDimensionsUserComment
current04:33, 14 November 201432 s, 672 × 512 (9.05 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 480P 1.17 Mbps Completed 22:26, 13 October 2018 36 s
VP9 360P 633 kbps Completed 22:26, 13 October 2018 28 s
VP9 240P 322 kbps Completed 22:26, 13 October 2018 34 s
WebM 360P 508 kbps Completed 04:34, 14 November 2014 23 s
QuickTime 144p (MJPEG) Not ready Unknown status

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