File:Plasmodium falciparum HSP70.tif

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Description
English: Localization of HSP70 in erythrocyte infected by Plasmodium falciparum. Figure 6 of article.


Caption from article: PfHsp70-x partially associates with Maurer’s clefts but not with knobs:

  • (A–B)
    • Panel I: the signal for PfHsp70-x (green) was obtained in the parasite compartment along with few punctate spots in the erythrocyte compartment.
    • Panel II: MAHRP1 (red) stained discrete foci representative of Maurer’s clefts in the erythrocyte periphery.
    • Panel III: the DIC image of the infected erythrocyte.
    • Panel IV: merged image overlaid with DIC image reveals that MAHRP1 and PfHsp70-x partially co-localize in the erythrocyte compartment, suggesting that PfHsp70-x possibly associates with Maurer’s clefts.
  • (C-D)
    • Panel I: the signal for PfHsp70-x (green) was obtained in the parasite compartment along with few punctate spots in the erythrocyte compartment.
    • Panel II: KAHRP (red), being a constituent of knobs, stained the entire erythrocyte membrane.
    • Panel III shows the DIC image of the infected erythrocyte.
    • Panel IV: no co-localization is observed between KAHRP and PfHsp70-x, suggesting that PfHsp70-x does not associate with knobs on the infected erythrocyte membrane.
Date
Source Grover, M., Chaubey, S., Ranade, S. & Tatu, U. 2013: Identification of an exported heat shock protein 70 in Plasmodium falciparum. Parasite, 20, 2. doi:10.1051/parasite/2012002
Author Grover, Manish; Chaubey, Shweta; Ranade, Shatakshi; Tatu, Utpal

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Parasite
Parasite
This file was published in the scientific journal Parasite. Their website states that all content of the journal including and after 2013 is published under the Creative Commons Attribution 4.0 license.

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