File:Permanent-Occlusion-of-Feeding-Arteries-and-Draining-Veins-in-Solid-Mouse-Tumors-by-Vascular-pone.0010282.s003.ogv
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Permanent-Occlusion-of-Feeding-Arteries-and-Draining-Veins-in-Solid-Mouse-Tumors-by-Vascular-pone.0010282.s003.ogv (Ogg Theora video file, length 2 min 33 s, 352 × 288 pixels, 129 kbps, file size: 2.35 MB)
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[edit]DescriptionPermanent-Occlusion-of-Feeding-Arteries-and-Draining-Veins-in-Solid-Mouse-Tumors-by-Vascular-pone.0010282.s003.ogv |
English: Blood flow in the tumor's FA and DV during Tookad-VTP. Blood flow was monitored in real-time using injected fluorescently-labeled erythrocytes (4-Di-10-ASP) from donor mice. No significant changes in flow were detected during the light control phase. Soon after VTP onset (time counter icon turns red), blood flow velocity in the main vessels decreased, until full vascular collapse at ∼60 sec. At tVTP = 2 min, FA flow still had not recovered and DV blood velocity dramatically decreased, while the vessels in the surrounding tissue (also exposed to light and drug) showed normal behavior. Reversed venous blood flow was evident at tVTP = 5 min. Selective, irreversible FA blood stasis and reversed venous blood flow remained until the end of data acquisition period, 30 min post-VTP onset. |
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Source | Video S3 from Madar-Balakirski N, Tempel-Brami C, Kalchenko V, Brenner O, Varon D, Scherz A, Salomon Y (2010). "Permanent Occlusion of Feeding Arteries and Draining Veins in Solid Mouse Tumors by Vascular Targeted Photodynamic Therapy (VTP) with Tookad". PLOS ONE. DOI:10.1371/journal.pone.0010282. PMID 20421983. PMC: 2858664. | ||
Author | Madar-Balakirski N, Tempel-Brami C, Kalchenko V, Brenner O, Varon D, Scherz A, Salomon Y | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 03:37, 17 November 2012 | 2 min 33 s, 352 × 288 (2.35 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Madar-Balakirski N, Tempel-Brami C, Kalchenko V, Brenner O, Varon D, Scherz A, Salomon Y |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
Image title | Blood flow in the tumor's FA and DV during Tookad-VTP. Blood flow was monitored in real-time using injected fluorescently-labeled erythrocytes (4-Di-10-ASP) from donor mice. No significant changes in flow were detected during the light control phase. Soon after VTP onset (time counter icon turns red), blood flow velocity in the main vessels decreased, until full vascular collapse at ?60 sec. At tVTP? |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2010 |
Categories:
- Microscopic images of Mus musculus circulatory system
- Vascular biology
- Magnetic resonance imaging videos
- Arteries
- Videos of coagulation
- Blood flow velocity
- Animal models of disease
- Videos of neoplasms
- Neovascularization
- Cell membrane permeability
- Photodynamic therapy
- Treatment outcomes
- Vasoconstriction
- Veins in animals
- Media from PLOS ONE