File:Molecular-dynamics-simulations-highlight-structural-and-functional-alterations-in-deafness-related-Movie1.ogv

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Molecular-dynamics-simulations-highlight-structural-and-functional-alterations-in-deafness-related-Movie1.ogv (Ogg multiplexed audio/video file, Theora/Vorbis, length 30 s, 258 × 360 pixels, 2.05 Mbps overall, file size: 7.44 MB)

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English: Steered molecular dynamics of K+ permeation. In this simulation, we force a K+ ion to permeate through the pore of Cx26WT and Cx26M34T hemichannels. The total PMFs for the two cases (black trace for wild type and red trace for the mutant) is shown in register with the permeating ion position (represented with its Van der Waals radius, in pink). The NTHs are highlighted in red, and two key residues are represented in ball and stick; T34 is color in green and K41 (corresponding to the maximum of the total PMF) in orange.
Date
Source Supplementary Movie S1 from Zonta F, Buratto D, Cassini C, Bortolozzi M, Mammano F (2014). "Molecular dynamics simulations highlight structural and functional alterations in deafness-related M34T mutation of connexin 26". Frontiers in Physiology. DOI:10.3389/fphys.2014.00085. PMID 24624091. PMC: 3941013.
Author Zonta F, Buratto D, Cassini C, Bortolozzi M, Mammano F
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This file was transferred to Wikimedia Commons from PubMed Central by way of the Open Access Media Importer.
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Date/TimeThumbnailDimensionsUserComment
current14:44, 17 March 201430 s, 258 × 360 (7.44 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 360P 643 kbps Completed 17:00, 3 September 2018 53 s
VP9 240P 325 kbps Completed 17:00, 3 September 2018 29 s
WebM 360P 503 kbps Completed 14:45, 17 March 2014 18 s
QuickTime 144p (MJPEG) Not ready Unknown status

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