File:Molecular-Architecture-of-the-Human-Mediator–RNA-Polymerase-II–TFIIF-Assembly-pbio.1000603.s016.ogv

English: Structure of Mediator–pol II–TFIIF. A 3D surface representation of the cryo-EM reconstruction of Mediator–pol II–TFIIF, rendered to 1.8 MDa, is shown in solid blue. The structure is rotated 360 degrees about the horizontal axis, followed by a rotation of 360 degrees about the vertical axis. The Mediator–pol II–TFIIF surface is then displayed as blue mesh with a pol II crystal structure (PDB 1Y1V) shown in red ribbon in its docked orientation. The cryo-EM structure and docked pol II are then rotated about the horizontal and vertical axis as before, with the rotation paused to highlight views of the complex shown in Figure 3. Scale bar represents 100 Å.