File:Model for cloacal septation.png
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[edit]DescriptionModel for cloacal septation.png | Figure 7. Model for cloacal septation. (A) E11.5 Bmp7lacZ/+ embryo stained with X-gal. Position of the cloacal section depicted in (B) is indicated with dashed line. (B) Signaling by Bmp7 from the URM (blue) activates JNK in the cloacal endoderm. Bmp7/JNK activity promotes cell survival, proliferation and apical-basal polarity of cell divisions in the endoderm (red arrows) which facilitates topological separation of the rectum and urethra. Apical-basal polarity of cell divisions is required for epithelial differentiation and expression of K14. doi:10.1371/journal.pone.0029372.g007 | ||
Date | |||
Source |
Xu K, Wu X, Shapiro E, Huang H, Zhang L, Hickling D, et al. (2012) Bmp7 Functions via a Polarity Mechanism to Promote Cloacal Septation. PLoS ONE 7(1): e29372. doi:10.1371/journal.pone.0029372 |
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Author | Kun Xu, Xinyu Wu, Ellen Shapiro, Honging Huang, Lixia Zhang, Duane Hickling, Yan Deng, Peng Lee, Juan Li, Herbert Lepor, Irina Grishina | ||
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© 2012 Xu et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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current | 17:39, 24 July 2024 | ![]() | 2,080 × 1,414 (996 KB) | Rasbak (talk | contribs) | {{Information |description='''Figure 7. Model for cloacal septation.''' (A) E11.5 ''Bmp7<sup>lacZ/+</sup>'' embryo stained with X-gal. Position of the cloacal section depicted in (B) is indicated with dashed line. (B) Signaling by Bmp7 from the URM (blue) activates JNK in the cloacal endoderm. Bmp7/JNK activity promotes cell survival, proliferation and apical-basal polarity of cell divisions in the endoderm (red arrows) which facilitates topological separation of the rectum and urethra. Apica... |
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