File:Mobilization-of-HIV-Spread-by-Diaphanous-2-Dependent-Filopodia-in-Infected-Dendritic-Cells-ppat.1002762.s013.ogv
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Size of this JPG preview of this OGG file: 800 × 548 pixels. Other resolutions: 320 × 219 pixels | 640 × 439 pixels | 1,024 × 702 pixels | 1,424 × 976 pixels.
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[edit]DescriptionMobilization-of-HIV-Spread-by-Diaphanous-2-Dependent-Filopodia-in-Infected-Dendritic-Cells-ppat.1002762.s013.ogv |
English: The PTAP (late domain) of HIV Gag is dispensible for VF formation. To synchronize immature virions at the plasma membrane of infected cells, we replaced the PTAP motif of the p6 domain in HIV Gag to LIRL. Cell free infectious HIV iGFP lacking the PTAP domain was possible, as HIV iGFP virus is rescued at the protein level using WT Gag and Gag-Pol as outlined in Fig. 1. Thus this approach provides PTAP-Tsg101 recruitment for the generation of infectious cell free virus. Scale bar is 6 µm and time is presented at the bottom left hand corner as per VideoS1. Video is representative of 4 independent infections and over 200 video acquisitions. |
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Source | Video S11 from Aggarwal A, Iemma T, Shih I, Newsome T, McAllery S, Cunningham A, Turville S (2012). "Mobilization of HIV Spread by Diaphanous 2 Dependent Filopodia in Infected Dendritic Cells". PLOS Pathogens. DOI:10.1371/journal.ppat.1002762. PMID 22685410. PMC: 3369929. | ||
Author | Aggarwal A, Iemma T, Shih I, Newsome T, McAllery S, Cunningham A, Turville S | ||
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 06:00, 14 November 2012 | 5.3 s, 1,424 × 976 (2.86 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Aggarwal A, Iemma T, Shih I, Newsome T, McAllery S, Cunningham A, Turville S |
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Usage terms | http://creativecommons.org/licenses/by/3.0/ |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2012-06 |