File:Lymphatic vessels develop in the postnatal ovary from around 10 dpn.png

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Figure 4. Lymphatic vessels develop in the postnatal ovary from around 10 dpn. A)

At 7 dpn, EGFP-positive vessels are observed in along one side of the uterine horn and in the ovarian ligaments, but the ovary (encircled) is still devoid of lymphatics. B) At 10 dpn, the ovary possesses a lymphatic network. Lymphatic vessels sprouting laterally at distinct regional distances from a pre-existing vasculature along the length of the uterus have almost encircled the entire uterine horn. C) At 14 dpn, the ovary possesses a distinct lymphatic network and the uterine horn has developed a strikingly segmented lymphatic network encircling the entire tissue D) The adult ovary maintain a high Prox1-RGFP expression and the uterine horn has developed a extensive mesh of lymphatic vessels. E) Prominent Prox1-EGFP positive vessels of the 9 week uterine horn also express endogenous PROX1, and F) the lymphatic marker NRP2, G) both overlapping with Prox1-EGFP expression. OL = ovarian ligament; U = uterine horn; scale bar = 200 µm.

https://doi.org/10.1371/journal.pone.0052620.g004
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Source https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0052620 Svingen T, François M, Wilhelm D, Koopman P (2012) Three-Dimensional Imaging of Prox1-EGFP Transgenic Mouse Gonads Reveals Divergent Modes of Lymphangiogenesis in the Testis and Ovary. PLoS ONE 7(12): e52620. https://doi.org/10.1371/journal.pone.0052620
Author Lim J, Maher GJ, Turner GDH, Dudka-Ruszkowska W, Taylor S, Meyts ER-D, et al.

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© 2012 Svingen et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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current20:23, 2 August 2024Thumbnail for version as of 20:23, 2 August 20243,439 × 2,585 (4.46 MB)Rasbak (talk | contribs){{Information |description=Figure 4. Lymphatic vessels develop in the postnatal ovary from around 10 dpn. A) At 7 dpn, EGFP-positive vessels are observed in along one side of the uterine horn and in the ovarian ligaments, but the ovary (encircled) is still devoid of lymphatics. B) At 10 dpn, the ovary possesses a lymphatic network. Lymphatic vessels sprouting laterally at distinct regional distances from a pre-existing vasculature along the length of the uterus have almost encircled the enti...

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