File:Live-Imaging-of-Innate-Immune-Cell-Sensing-of-Transformed-Cells-in-Zebrafish-Larvae-Parallels-pbio.1000562.s007.ogv

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English: Supporting movies for Figure 3. (A) is a time-lapse movie made from a Fli:eGFP/kita:GalTA4/UAS:V12RASeGFP+ larva that shows the earliest recognition of V12RAS-transformed cells by Fli:eGFP+ leukocytes at the initial stage of transformed cell expansion. Green arrows indicate V12RAS+ mucus-secreting cells. These cells express V12RASeGFP and so GFP appears membrane-located in these cells. Leukocytes are motile and labeled by Fli:eGFP, and the GFP signal in these cells has a pale cytoplasmic distribution. (B) shows an example of how LysC:DsRed+ leukocytes respond to V12RAS+ clones at their “early developmental” stage. (C) shows an example of how LysC:DsRed+ cells respond to a “late developmental” stage V12RAS+ clone. Note how LysC:DsRed+ cells stay with the clone for a prolonged period.
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Source Video S5 from Feng Y, Santoriello C, Mione M, Hurlstone A, Martin P (2010). "Live Imaging of Innate Immune Cell Sensing of Transformed Cells in Zebrafish Larvae: Parallels between Tumor Initiation and Wound Inflammation". PLOS Biology. DOI:10.1371/journal.pbio.1000562. PMID 21179501. PMC: 3001901.
Author Feng Y, Santoriello C, Mione M, Hurlstone A, Martin P
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This file was published in a Public Library of Science journal. Their website states that the content of all PLOS journals is published under the Creative Commons Attribution 4.0 license (or its previous version depending on the publication date), unless indicated otherwise.
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Date/TimeThumbnailDimensionsUserComment
current00:49, 31 October 201218 s, 1,536 × 512 (3.37 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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