File:Ligand-specific-endocytic-dwell-times-control-functional-selectivity-of-thecannabinoid-receptor-1-ncomms5589-s2.ogv
Ligand-specific-endocytic-dwell-times-control-functional-selectivity-of-thecannabinoid-receptor-1-ncomms5589-s2.ogv (Ogg Theora video file, length 3.3 s, 294 × 294 pixels, 339 kbps, file size: 137 KB)
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[edit]DescriptionLigand-specific-endocytic-dwell-times-control-functional-selectivity-of-thecannabinoid-receptor-1-ncomms5589-s2.ogv |
English: Supplementary Movie 1 Surface SEP-CB1Rs quenching. Simultaneous dual fluorescence TIRF microscopy
series (10Hz) from a HEK cell co-expressing SEP-CB1R and RFP-β-arrestin-2 were incubated with 5 μM WIN 55,212-2 to induce receptor clustering and endocytosis. Perfusion of MES pH5.5 resulted in a rapid decrease in SEP-CB1R fluorescence. |
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Source | Video file from Flores-Otero J, Ahn K, Delgado-Peraza F, Mackie K, Kendall D, Yudowski G (2014). "Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1". Nature Communications. DOI:10.1038/ncomms5589. PMID 25081814. PMC: 4227836. | ||
Author | Flores-Otero J, Ahn K, Delgado-Peraza F, Mackie K, Kendall D, Yudowski G | ||
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![]() ![]() This file is licensed under the Creative Commons Attribution 4.0 International license.
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current | 13:10, 2 November 2016 | 3.3 s, 294 × 294 (137 KB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Short title | Supplementary Movie 1 |
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Author | Flores-Otero J, Ahn K, Delgado-Peraza F, Mackie K, Kendall D, Yudowski G |
Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | Surface SEP-CB1Rs quenching. Simultaneous dual fluorescence TIRF microscopy
series (10Hz) from a HEK cell co-expressing SEP-CB1R and RFP-β-arrestin-2 were incubated with 5 μM WIN 55,212-2 to induce receptor clustering and endocytosis. Perfusion of MES pH5.5 resulted in a rapid decrease in SEP-CB1R fluorescence. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2014-08-01 |