File:In-vivo-single-molecule-imaging-identifies-altered-dynamics-of-calcium-channels-in-dystrophin-ncomms5974-s6.ogv

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Original file ‎(Ogg Theora video file, length 9.1 s, 738 × 738 pixels, 25.87 Mbps, file size: 27.96 MB)

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English: Supplementary Movie 5 HILO dCALM imaging of VDCC in a normal, bead-immobilized worm where some muscles undergo active contractions (arrowhead). VDCC are strongly stabilized in nanodomains and at each contraction the inter-distance between nanodomains transiently decreases before increasing back during relaxation. This consecutive reductions and augmentations of VDCC nanodomains inter-distances suggest that the sarcolemma undergoes periodic deformations at each contraction/relaxation cycle, reminiscent of sarcolemma festooning. Movie acquired at 80 ms per frame and played back at video rate.
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Source Video file from Zhan H, Stanciauskas R, Stigloher C, Dizon K, Jospin M, Bessereau J, Pinaud F (2014). "In vivo single-molecule imaging identifies altered dynamics of calcium channels in dystrophin-mutant C. elegans". Nature Communications. DOI:10.1038/ncomms5974. PMID 25232639. PMC: 4199201.
Author Zhan H, Stanciauskas R, Stigloher C, Dizon K, Jospin M, Bessereau J, Pinaud F
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current09:18, 2 November 20169.1 s, 738 × 738 (27.96 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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VP9 720P 2.49 Mbps Completed 16:39, 29 August 2018 38 s
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