File:In-Vivo-Approaches-Reveal-a-Key-Role-for-DCs-in-CD4+-T-Cell-Activation-and-Parasite-Clearance-ppat.1004598.s014.ogv

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In-Vivo-Approaches-Reveal-a-Key-Role-for-DCs-in-CD4+-T-Cell-Activation-and-Parasite-Clearance-ppat.1004598.s014.ogv (Ogg Theora video file, length 8.0 s, 512 × 515 pixels, 3.25 Mbps, file size: 3.1 MB)

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English: CD4 + T cell / DC dynamics in the spleen of a recently infected mouse. Time-lapse images show a representative 3D region of the subcapsular spleen in a B6.CD11c-YFP mouse adoptively transferred with polyclonal CD4+ T cells from B6.CFP mice, starting 24 h after i.v. infection with 1 × 108 mature mCherry-Pc iRBCs. The video shows YFP+ cells (green) that are slightly more motile, still making protrusions and actively internalizing parasites (red). CD4+ T cells (blue) are less motile and are making more stable contacts with YFP+ cells. Images were acquired with Z-steps of 4 µm (total Z = 28 µm) for 60 min at 1 frame/15 s of live imaging. The video is shown at 15 frames/s with maximum color intensity.
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Source S7 Video from Borges da Silva H, Fonseca R, Cassado A, Machado de Salles É, de Menezes M, Langhorne J, Perez K, Cuccovia I, Ryffel B, Barreto V, Marinho C, Boscardin S, Álvarez J, D’Império-Lima M, Tadokoro C (2015). "In Vivo Approaches Reveal a Key Role for DCs in CD4+ T Cell Activation and Parasite Clearance during the Acute Phase of Experimental Blood-Stage Malaria". PLOS Pathogens. DOI:10.1371/journal.ppat.1004598. PMID 25658925. PMC: 4450059.
Author Borges da Silva H, Fonseca R, Cassado A, Machado de Salles É, de Menezes M, Langhorne J, Perez K, Cuccovia I, Ryffel B, Barreto V, Marinho C, Boscardin S, Álvarez J, D’Império-Lima M, Tadokoro C
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Date/TimeThumbnailDimensionsUserComment
current17:36, 12 October 20168.0 s, 512 × 515 (3.1 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 480P 1.06 Mbps Completed 15:11, 29 August 2018 9.0 s
VP9 360P 574 kbps Completed 15:11, 29 August 2018 9.0 s
VP9 240P 314 kbps Completed 15:11, 29 August 2018 6.0 s
WebM 360P 516 kbps Completed 17:36, 12 October 2016 6.0 s
QuickTime 144p (MJPEG) Not ready Unknown status

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