File:Glutamate-Bound-NMDARs-Arising-from-In-Vivo-like-Network-Activity-Extend-Spatio-temporal-pcbi.1003590.s010.ogv
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Glutamate-Bound-NMDARs-Arising-from-In-Vivo-like-Network-Activity-Extend-Spatio-temporal-pcbi.1003590.s010.ogv (Ogg Theora video file, length 57 s, 800 × 600 pixels, 380 kbps, file size: 2.57 MB)
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[edit]DescriptionGlutamate-Bound-NMDARs-Arising-from-In-Vivo-like-Network-Activity-Extend-Spatio-temporal-pcbi.1003590.s010.ogv |
English: Movie 2 shows the membrane voltage in the Layer 5 Pyramidal cell model during nearly synchronous stimulus evoked synaptic stimulation of 100 synapses spatially distributed over the apical tuft (10 Hz from 100–200 ms) under 3 conditions: 1) Control with no background activity. 2) With background activity from 1500 excitatory synapses firing randomly at 0.85 Hz3) With balanced background synaptic input including inhibition from SOM-like (GABAA) and NGF-like (GABAA and GABAB) mediated inhibition. Only in the case of stimulation in the presence of excitatory input did the spatially distributed synaptic input trigger somatic action potentials which back propagates into the apical tree. |
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Source | Movie S2 from Farinella M, Ruedt D, Gleeson P, Lanore F, Silver R (2014). "Glutamate-Bound NMDARs Arising from In Vivo-like Network Activity Extend Spatio-temporal Integration in a L5 Cortical Pyramidal Cell Model". PLOS Computational Biology. DOI:10.1371/journal.pcbi.1003590. PMID 24763087. PMC: 3998913. | ||
Author | Farinella M, Ruedt D, Gleeson P, Lanore F, Silver R | ||
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This file is licensed under the Creative Commons Attribution 4.0 International license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 08:34, 7 May 2014 | 57 s, 800 × 600 (2.57 MB) | McZusatz (talk | contribs) | from src (uploaded using chunked upload script) | |
07:21, 3 May 2014 | 0.0 s (2.82 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
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