File:Glioblastoma-A-Pathogenic-Crosstalk-between-Tumor-Cells-and-Pericytes-pone.0101402.s015.ogv
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Glioblastoma-A-Pathogenic-Crosstalk-between-Tumor-Cells-and-Pericytes-pone.0101402.s015.ogv (Ogg Theora video file, length 12 s, 418 × 461 pixels, 1.17 Mbps, file size: 1.71 MB)
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[edit]DescriptionGlioblastoma-A-Pathogenic-Crosstalk-between-Tumor-Cells-and-Pericytes-pone.0101402.s015.ogv |
English: GBM cells modify the contractility of pericytes plated on laminin-coated silicone substrates. The area occupied by Far-Red (magenta color) dextran+-U87 cells is delimited by the yellow dashed line (analogous to a graft/host margin). Tumor-flectopodia (white arrows) are associated with modifications of the wrinkling substrate (green arrowheads). Red arrows and red arrowheads indicate flectopodia extensions emanating from groups of GBM-cells, at progressively later times. The altered position of the yellow dashed-line shows the modification of the co-opting-tumor front (first and final positions are compared in the final video-frame). Yellow arrows indicate the difference in the pericyte wrinkling activity at the interacting front. Δtime: 10 minutes; time: 8 hours; rate: 3 fps. |
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Source | Movie S4 from Caspani E, Crossley P, Redondo-Garcia C, Martinez S (2014). "Glioblastoma: A Pathogenic Crosstalk between Tumor Cells and Pericytes". PLOS ONE. DOI:10.1371/journal.pone.0101402. PMID 25032689. PMC: 4102477. | ||
Author | Caspani E, Crossley P, Redondo-Garcia C, Martinez S | ||
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![]() ![]() This file is licensed under the Creative Commons Attribution 4.0 International license.
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 19:06, 14 October 2016 | 12 s, 418 × 461 (1.71 MB) | Open Access Media Importer Bot (talk | contribs) | Automatically uploaded media file from Open Access source. Please report problems or suggestions here. |
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Author | Caspani E, Crossley P, Redondo-Garcia C, Martinez S |
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Usage terms | http://creativecommons.org/licenses/by/4.0/ |
Image title | GBM cells modify the contractility of pericytes plated on laminin-coated silicone substrates. The area occupied by Far-Red (magenta color) dextran+-U87 cells is delimited by the yellow dashed line (analogous to a graft/host margin). Tumor-flectopodia (white arrows) are associated with modifications of the wrinkling substrate (green arrowheads). Red arrows and red arrowheads indicate flectopodia extensions emanating from groups of GBM-cells, at progressively later times. The altered position of the yellow dashed-line shows the modification of the co-opting-tumor front (first and final positions are compared in the final video-frame). Yellow arrows indicate the difference in the pericyte wrinkling activity at the interacting front. Δtime: 10 minutes; time: 8 hours; rate: 3 fps. |
Software used | Xiph.Org libtheora 1.1 20090822 (Thusnelda) |
Date and time of digitizing | 2014 |
Categories:
- Videos of cell biology
- Cell motility
- Microfilaments
- Videos of cell types
- Animal cells
- Videos of CD44
- Videos of glioblastoma
- Tumor cell line
- Cell surface extensions
- Nude mice
- Transgenic mice
- Neoplasm transplantation
- Neoplastic stem cells
- Neovascularization
- Small interfering RNA
- Heterologous transplantation
- Videos of CDC42
- Media from PLOS ONE
- Pericyte