File:Evolution of XIST-ru.tif
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[edit]DescriptionEvolution of XIST-ru.tif |
English: The Xist gene evolved from a protein-coding gene and a set of transposable elements. Blue box – exons originating from Lnx3; red box - exons originating from transposable elements; dashed box – pseudoexons. Русский: Происхождение гена Xist из последовательностей белоккодирующего гена Lnx3 и мобильных элементов разных классов. Синие прямоугольники – экзоны, эволюционировавшие из гена Lnx3; красные прямоугольники – экзоны, произошедшие из мобильных элементов. Заштрихованные синие и красные прямоугольники – последовательности экзонов, выявляющиеся в геноме, но не входящие в состав транскрипта Xist у данного вида.
Консенсус – предположительная предковая структура гена Xist. Для генов Xist человека (Homo sapiens) и мыши (Mus musculus) приведена нумерация экзонов (m1–m8 – экзоны Xist мыши, h1–h8 – экзоны Xist человека) (Шевченко А. И., Захарова И. С., Закиян С. М. Эволюционный путь процесса инактивации Х-хромосомы у млекопитающих // Acta Naturae. — 2013. — Т. 5. — № 2. — С. 40-54) |
Date | |
Source | Elisaphenko et al. A dual origin of the Xist gene from a protein-coding gene and a set of transposable elements. PLoS One. 2008 Jun 25;3(6):e2521. doi: 10.1371/journal.pone.0002521. |
Author | Elisaphenko EA, Kolesnikov NN, Shevchenko AI, Rogozin IB, Nesterova TB, Brockdorff N, Zakian SM. |
This is a retouched picture, which means that it has been digitally altered from its original version. Modifications: translated. The original can be viewed here: Evolution of Xist gene.tif: . Modifications made by Abogomazova.
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File change date and time | 20:42, 10 June 2013 |
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