File:Emergence-of-Large-Scale-Cell-Morphology-and-Movement-from-Local-Actin-Filament-Growth-Dynamics-pbio.0050233.sv002.ogv

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Emergence-of-Large-Scale-Cell-Morphology-and-Movement-from-Local-Actin-Filament-Growth-Dynamics-pbio.0050233.sv002.ogv (Ogg Theora video file, length 6.8 s, 652 × 327 pixels, 338 kbps, file size: 280 KB)

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English: Nascent Lamellipodia Emerge with Rough Edges and Rapidly Acquire a Smooth Morphology A glass micropipette, acting as a barrier, was lowered into the path of movement of a migrating, coherent keratocyte overexpressing EGFP-VASP. When the keratocyte reaches the barrier, the lamellipodium temporarily stops protruding forward, while EGFP-VASP becomes displaced from the edge of the region in contact with the barrier. When the micropipette barrier is removed (between 0:57 and 1:00), the leading edge of the lamellipodium immediately resumes protrusion and appears rough with several protruding microregions enriched in EGFP-VASP. Only 18 s after removal of the barrier, the keratocyte's original shape and uniform EGFP-VASP localization at the leading edge are restored. Time = min:s. Scale bar = 25 μm.
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Source Video S2 from Lacayo C, Pincus Z, VanDuijn M, Wilson C, Fletcher D, Gertler F, Mogilner A, Theriot J (2007). "Emergence of Large-Scale Cell Morphology and Movement from Local Actin Filament Growth Dynamics". PLOS Biology. DOI:10.1371/journal.pbio.0050233. PMID 17760506. PMC: 1951782.
Author Lacayo C, Pincus Z, VanDuijn M, Wilson C, Fletcher D, Gertler F, Mogilner A, Theriot J
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Date/TimeThumbnailDimensionsUserComment
current14:30, 16 November 20126.8 s, 652 × 327 (280 KB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 360P 136 kbps Completed 19:03, 25 August 2018 3.0 s
VP9 240P 73 kbps Completed 19:03, 25 August 2018 2.0 s
WebM 360P 404 kbps Completed 01:02, 19 November 2012 2.0 s
QuickTime 144p (MJPEG) 235 kbps Completed 02:09, 24 October 2024 1.0 s

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