File:Electron-Tomography-of-HIV-1-Infection-in-Gut-Associated-Lymphoid-Tissue-ppat.1003899.s010.ogv

English: Intercalating infected cell with budding profile contacting an adjacent cell. A large-area tomographic reconstruction comprising a 5.4 µm×3.6 µm×0.35 µm volume of a colon crypt. The region contained three cells: two crypt cells and a third cell intercalating between them. The intercalating cell is presumably a dendritic cell or macrophage due to its convoluted projections (see Figure 5B). It was HIV-1–infected and displayed four budding profiles within the reconstructed volume. One such bud (black arrow), shown in detain in the latter half of the movie, crossed the intercellular space to form a presumptive virological synapse by directly contacting the adjacent cell (red arrowheads).