File:EGFR-oligomerization-organizes-kinase-active-dimers-into-competent-signalling-platforms-ncomms13307-s2.ogv

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English: Supplementary Movie 1 Single particle tracking of EGFR on live CHO cells at 37°C. CHO cells stably expressing 105 wild type EGFR/cell were treated with a 4 nM CF640R fluorophore-conjugated Affibody solution at 37°C and tracked as previously described7. The multiple steps during photobleaching shown by individual spots indicate that receptors form high order oligomers prior to the EGF stimulus.
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Source Video file from Needham S, Roberts S, Arkhipov A, Mysore V, Tynan C, Zanetti-Domingues L, Kim E, Losasso V, Korovesis D, Hirsch M, Rolfe D, Clarke D, Winn M, Lajevardipour A, Clayton A, Pike L, Perani M, Parker P, Shan Y, Shaw D, Martin-Fernandez M (2016). "EGFR oligomerization organizes kinase-active dimers into competent signalling platforms". Nature Communications. DOI:10.1038/ncomms13307. PMID 27796308. PMC: 5095584.
Author Needham S, Roberts S, Arkhipov A, Mysore V, Tynan C, Zanetti-Domingues L, Kim E, Losasso V, Korovesis D, Hirsch M, Rolfe D, Clarke D, Winn M, Lajevardipour A, Clayton A, Pike L, Perani M, Parker P, Shan Y, Shaw D, Martin-Fernandez M
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Date/TimeThumbnailDimensionsUserComment
current02:27, 2 February 201736 s, 1,024 × 768 (20.65 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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Format Bitrate Download Status Encode time
VP9 720P 1.79 Mbps Completed 04:03, 25 August 2018 1 min 20 s
Streaming 720p (VP9) 1.79 Mbps Completed 15:08, 15 March 2024 2.0 s
VP9 480P 999 kbps Completed 04:02, 25 August 2018 53 s
Streaming 480p (VP9) 999 kbps Completed 02:19, 6 February 2024 1.0 s
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