File:Control of late mitotic events by the APC.pdf

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Control_of_late_mitotic_events_by_the_APC.pdf (750 × 300 pixels, file size: 422 KB, MIME type: application/pdf)

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Control of late mitotic events by the APC

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English: M–Cdk activity promotes the events of early mitosis, resulting in the metaphase alignment of sister chromatids on the spindle. M–Cdk activity also promotes the activation of APCCdc20, which triggers anaphase and mitotic exit by stimulating the destruction of regulatory proteins, such as securin and cyclins, that govern these events. By promoting cyclin destruction and thus Cdk inactivation, APCCdc20 also triggers activation of APCCdh1, thereby ensuring continued APC activity in G1.[1]
Date
Source The Cell Cycle. Principles of Control.
Author David O Morgan

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© The copyright holder of this file allows anyone to use it for any purpose, provided that the copyright holder is properly attributed. Redistribution, derivative work, commercial use, and all other use is permitted.

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current02:33, 8 April 2020Thumbnail for version as of 02:33, 8 April 2020750 × 300 (422 KB)Rob Hurt (talk | contribs)Uploaded a work by David O Morgan from The Cell Cycle. Principles of Control. with UploadWizard

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